Applications of guanine quartets in nanotechnology and chemical biology

L Stefan, D Monchaud - Nature Reviews Chemistry, 2019 - nature.com
Guanine and related nucleobases such as guanosine, deoxyguanosine and isoguanosine
are notable molecular tools for designing functional supramolecular assemblies. This …

Peptide and glycopeptide dendrimers and analogous dendrimeric structures and their biomedical applications

J Sebestik, P Niederhafner, J Jezek - Amino acids, 2011 - Springer
The size of information that can be stored in nucleic acids, proteins, and carbohydrates was
calculated. The number of hexamers for peptides is 64,000,000 (20 6) and seems to be …

Deciphering the DNAzyme activity of multimeric quadruplexes: insights into their actual role in the telomerase activity evaluation assay

L Stefan, F Denat, D Monchaud - Journal of the American …, 2011 - ACS Publications
The end of human telomeres is comprised of a long G-rich single-stranded DNA (known as
3′-overhang) able to adopt an unusual three-dimensional “beads-on-the-string” …

[PDF][PDF] Tri‐G‐quadruplex: controlled assembly of a G‐quadruplex structure from three G‐rich strands

J Zhou, A Bourdoncle, F Rosu, V Gabelica… - Angewandte …, 2012 - academia.edu
Guanine-rich oligonucleotides are able to self-associate to form G-quadruplexes, a higher-
order DNA structure, in the presence of certain cations (typically Na+ and K+ ions).[1–3] G …

Hydrogen‐Bonded Macrocyclic Supramolecular Systems in Solution and on Surfaces

MJ Mayoral, N Bilbao… - ChemistryOpen, 2016 - Wiley Online Library
Cyclization into closed assemblies is the most recurrent approach to realize the noncovalent
synthesis of discrete, well‐defined nanostructures. This review article particularly focuses on …

Guidelines for the assembly of hydrogen-bonded macrocycles

F Aparicio, MJ Mayoral, C Montoro-García… - Chemical …, 2019 - pubs.rsc.org
The formation of well-defined, discrete self-assembled architectures relies on the interplay
between non-covalent interactions and cooperative phenomena. In particular, chelate or …

Template‐Assembled Synthetic G‐Quadruplex (TASQ): A Useful System for Investigating the Interactions of Ligands with Constrained Quadruplex Topologies

P Murat, R Bonnet, A Van der Heyden… - … A European Journal, 2010 - Wiley Online Library
A new biomolecular device for investigating the interactions of ligands with constrained DNA
quadruplex topologies, using surface plasmon resonance (SPR), is reported. Biomolecular …

Stabilisation of non-canonical structures of nucleic acids by metal ions and small molecules

T Biver - Coordination Chemistry Reviews, 2013 - Elsevier
A general overview is provided about the recent and state of the art advances in the field of
metal ions, metal complexes and small aromatic molecules use as stabilising agents for non …

DOTASQ as a prototype of nature-inspired G-quadruplex ligand

L Stefan, A Guedin, S Amrane, N Smith… - Chemical …, 2011 - pubs.rsc.org
DOTASQ (for DOTA-templated Synthetic G-quartet) is the first prototype of nature-inspired G-
quadruplex ligand: its design, founded on a possible intramolecular G-quartet formation …

Biomimetic, smart, and multivalent ligands for G-quadruplex isolation and bioorthogonal imaging

FR Sperti, T Charbonnier, P Lejault, J Zell… - ACS Chemical …, 2021 - ACS Publications
G-quadruplexes (G4s) continue to gather wide attention in the field of chemical biology as
their prevalence in the human genome and transcriptome strongly suggests that they play …