Recently, medicinal peptide molecules are of great interest to many international
pharmaceutical companies, mainly because of their relatively lower research costs, shorter …

Peptides are not only useful models for the structural understanding of protein folding and
stability but also provide promising therapeutic avenues for the treatment of numerous …

Although interest in stabilized α-helical peptides as next-generation therapeutics for
modulating biomolecular interfaces is increasing, peptides have limited functionality and …

Because organic molecules and materials are generally insensitive or weakly sensitive to
magnetic fields, a certain means to enhance their magnetic responsiveness needs to be …

Disrupting the interaction between HIF1α and p300 is a promising strategy to modulate the
hypoxia response of tumor cells. Herein, we designed a constrained peptide inhibitor …

Cyclic peptides that modulate protein–protein interactions can be valuable therapeutic
candidates if they can be delivered intact to their target proteins in cells. Here we …

Determination of the solution conformation of both small organic molecules and peptides in
water remains a substantial hurdle in using NMR solution conformations to guide drug …

A 26-residue peptide BimBH3 binds indiscriminately to multiple oncogenic Bcl2 proteins that
regulate apoptosis of cancer cells. Specific inhibition of the BimBH3-Bcl2A1 protein–protein …

Coiled coils (CCs) are powerful supramolecular building blocks for biomimetic materials,
increasingly used for their mechanical properties. Here, we introduce helix‐inducing …

Lactate dehydrogenases (LDHs) are tetrameric enzymes of major significance in cancer
metabolism as well as promising targets for cancer therapy. However, their wide and polar …