Recent Developments in the Ruthenium‐Catalyzed Azide Alkyne Cycloaddition (RuAAC) Reaction
F Ferrara, T Beke‐Somfai… - European Journal of …, 2024 - Wiley Online Library
The ruthenium‐catalyzed azide‐alkyne cycloaddition (RuAAC) gives access to 1, 5‐
disubstitued triazoles in a single atom‐economical step and offers advantages compared to …
disubstitued triazoles in a single atom‐economical step and offers advantages compared to …
Recent synthetic strategies for the functionalization of fused bicyclic heteroaromatics using organo-Li,-Mg and-Zn reagents
V Dhayalan, VS Dodke, MP Kumar… - Chemical Society …, 2024 - pubs.rsc.org
This review highlights the use of functionalized organo-Li,-Mg and-Zn reagents for the
construction and selective functionalization of 5-and 6-membered fused bicyclic …
construction and selective functionalization of 5-and 6-membered fused bicyclic …
Access to Artemisinin–Triazole Antimalarials via Organo-Click Reaction: High In Vitro/In Vivo Activity against Multi-Drug-Resistant Malaria Parasites
L Herrmann, M Leidenberger, HC Quadros, BW Grau… - JACS Au, 2024 - ACS Publications
Malaria is one of the most widespread diseases worldwide. Besides a growing number of
people potentially threatened by malaria, the consistent emergence of resistance against …
people potentially threatened by malaria, the consistent emergence of resistance against …
Synthesis of Novel Artemisinin, Ciprofloxacin, and Norfloxacin Hybrids with Potent Antiplasmodial Activity
G Vamvoukaki, AI Antoniou, M Baltas, E Mouray… - Antibiotics, 2024 - mdpi.com
The synthesis and antiplasmodial evaluation of new hybrids combining the pharmacophore
structures of artemisinin, ciprofloxacin or norfloxacin, and 7-chloroquinoline are reported in …
structures of artemisinin, ciprofloxacin or norfloxacin, and 7-chloroquinoline are reported in …
Characterization of antimalarial activity of artemisinin-based hybrid drugs
HC Quadros, L Herrmann, J Manaranche… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
In response to the spread of artemisinin (ART) resistance, ART-based hybrid drugs were
developed, and their activity profile was characterized against drug-sensitive and drug …
developed, and their activity profile was characterized against drug-sensitive and drug …
Differences in the permeation of Licoricchalcone A-polysaccharide self-assembled nanoparticles on healthy and DNCB-induced atopic dermatitis in Balb/c mice
L Chen, Y Xue, F Wang, R Song, YW Zhu, J Ning… - International Journal of …, 2024 - Elsevier
Nanoformulation have been widely used in skin and transdermal drug delivery. However,
the differences in integral nanoparticles absorption in healthy and diseased skin have not …
the differences in integral nanoparticles absorption in healthy and diseased skin have not …
Discovery of Di (het) arylmethane and Dibenzoxanthene Derivatives as Potential Anticancer Agents
A Smolobochkin, D Niyazova, A Gazizov… - International Journal of …, 2024 - mdpi.com
A family of bifunctional dihetarylmethanes and dibenzoxanthenes is assembled via a
reaction of acetals containing a 2-chloroacetamide moiety with phenols and related oxygen …
reaction of acetals containing a 2-chloroacetamide moiety with phenols and related oxygen …
Design, synthesis, characterization and biological evaluation of coumarin bound 1, 2, 3-triazoles using click chemistry
In an endeavor to invent new antimalarial and antimicrobial agents, a series of coumarin
bound 1, 4-disubstituted 1, 2, 3-triazoles was synthesized through Cu (I)-promoted click …
bound 1, 4-disubstituted 1, 2, 3-triazoles was synthesized through Cu (I)-promoted click …
[PDF][PDF] AVALIAÇÃO FARMACOLÓGICA DO COMPLEXO DE OURO AUPAQ (2) PARA O TRATAMENTO DA MALÁRIA EXPERIMENTAL
MDACB SILVA - arca.fiocruz.br
RESUMO INTRODUÇÃO: Os compostos de ouro, a exemplo do auranofino, têm potencial
antiparasitário na malária por inibirem a atividade enzimática das TrxRs, todavia, estes são …
antiparasitário na malária por inibirem a atividade enzimática das TrxRs, todavia, estes são …