Advances in immunosuppressive agents based on signal pathway

Z Xu, M Chu - Frontiers in Pharmacology, 2022 - frontiersin.org
Immune abnormality involves in various diseases, such as infection, allergic diseases,
autoimmune diseases, as well as transplantation. Several signal pathways have been …

Insights Into the Role of Copper in Neurodegenerative Diseases and the Therapeutic Potential of Natural Compounds

G Zhong, X Wang, J Li, Z Xie, Q Wu… - Current …, 2024 - ingentaconnect.com
Neurodegenerative diseases encompass a collection of neurological disorders originating
from the progressive degeneration of neurons, resulting in the dysfunction of neurons …

Resveratrol mitigates cerebral ischemic injury by altering levels of trace elements, toxic metal, lipid peroxidation, and antioxidant activity

JH Ro, CC Liu, MC Lin - Biological Trace Element Research, 2021 - Springer
Cerebral ischemia causes increased oxidative stress due to the overproduction of reactive
oxygen species. The polyphenol compound resveratrol exerts neuroprotective effects …

Transcriptome analysis of the response of four immune related organs of tilapia (Oreochromis niloticus) to the addition of resveratrol in feed

W Ye, Y Zheng, Y Sun, Q Li, H Zhu, G Xu - Fish & Shellfish Immunology, 2023 - Elsevier
Resveratrol (RES) has been found to have immunological enhancement effects on
Oreochromis niloticus. In O. nilocticus, the liver, spleen and kidney act as immune target …

[HTML][HTML] The antioxidant effect of Aronia melanocarpa extract in rats oxidative stress induced by cisplatin administration

AO Doma, RT Cristina, E Dumitrescu, D Degi… - Journal of Trace …, 2023 - Elsevier
Background The reactive oxygen species generated by numerous xenobiotic substances
has as consequences the impairment of different organs normal function. Many plants pose …

[HTML][HTML] Homeostatic changes of trace elements in diazinon toxicity in rat model: The beneficial role of resveratrol

M Esfahani, F Mehri - Toxicology Reports, 2024 - Elsevier
Background and objectives Diazinon (DZN) is a cholinesterase inhibitor widely used to
relieve agricultural pests and upgrade the productivity of crops. Resveratrol (Res), as a …

Potential protection of resveratrol-tempeh against nephrotoxic and hepatotoxic histological damage in mice induced by aluminum

Y Irnidayanti, SAJ Wisaksono, W Darmanto, M Narayan… - Tissue and Cell, 2024 - Elsevier
Aluminum is a widely distributed metal that, while generally safe at low levels, can become
toxic when accumulated in the body. Its exposure is daily through various sources, including …

Effect of copper and selenium supplementation on the level of elements in rats' femurs under neoplastic conditions

D Skrajnowska, A Jagielska, A Ruszczyńska… - Nutrients, 2022 - mdpi.com
A study was conducted to determine the effect of long-term supplementation with selenium
and copper, administered at twice the level used in the standard diet of rats, on the content …

Quercetin Beneficial Role in the Homeostatic Variation of Certain Trace Elements in Dyslipidemic Mice

F Muselin, RT Cristina, E Dumitrescu… - Evidence‐Based …, 2022 - Wiley Online Library
Background. Quercetin's role in the homeostasis of certain trace elements in dyslipidemia
induced in mice was assessed. Methods. Forty BALB/c mice were allocated into 4 groups as …

Ovarian toxicity induced by aluminum chloride: alteration of Cyp19a1, Pcna, Puma, and Map1lc3b genes expression

FR Mansour, M Nabiuni, E Amini - Toxicology, 2022 - Elsevier
Aluminum (Al) is an abundant metal with wide application in our daily lives including
medicine, industry, cosmetics, and packaging. After entrance to the body, aluminum binds to …