The lens is an avascular organ that is supported by an internal circulation of water and
solutes. This circulation is driven by ion pumps, channels and transporters in epithelial cells …

Lens, an avascular tissue involved in light transmission, generates an internal
microcirculatory system to promote ion and fluid circulation, thus providing nutrients to …

High levels of reactive oxygen species such as hydrogen peroxide (H 2 O 2) cause oxidative
stress in the lens and lead to cataractogenesis. The present investigation was undertaken to …

Aquaporins are integral membrane proteins which are also known as water channel
proteins. They aid quick transportation of water across membranes and are important in …

Biology is about structure. Structures within structures. Organs within animals, tissues within
organs, cells within tissues, and molecules, often proteins within cells. The structures are so …

Clouding of the eye lens or cataract is an age-related anomaly that affects middle-aged
humans. Exploration of the etiology points to a great extent to oxidative stress due to …

Aquaporins (AQPs) are a family of membrane water channels that basically function as
regulators of intracellular and intercellular water flow. To date, 13 AQPs, distributed widely in …

Purpose Glutathione peroxidase 1 (GPX1) and catalase are expressed in the lens epithelial
cells and cortical fiber cells, where they detoxify H2O2 to reduce oxidative stress, which is a …

This investigation was undertaken to find out whether the positive charges in the
Extracellular Loops A (ELA) and C (ELC) of Aquaporin 0 (AQP0) are involved in lens fiber …

The cataractogenesis process and the novel mechanisms involved in its progression make
us question that the only solution today presented for its resolution is through a surgical …