T cell activation, proliferation, and differentiation into effector and memory states involve
massive remodeling of T cell size and molecular content and create a massive increase in …

Autophagy is a robust cellular mechanism for disposing of harmful molecules or recycling
them to cells, which also regulates physiopathological processes in cornea. Dysregulated …

A hallmark of HIV-1 infection is chronic inflammation, even in patients treated with
antiretroviral therapy (ART). Chronic inflammation drives HIV-1 pathogenesis, leading to …

Ethnopharmacological relevance A key event in the pathogenesis of acute-on-chronic liver
failure (ACLF) is the imbalance in the systemic immune response; immunosuppression in …

Abstract Metastatic Renal Cell Carcinoma (mRCC) remains incurable, despite the current
checkpoint-blockade-driven, limited overall response rate. The CD8+ memory T cells can …

Pomegranate peel extract (PoPEx) has been shown to have antioxidant and anti-
inflammatory properties, but its effect on the adaptive immune system has not been …

Nucleus accumbens‐associated protein 1 (NAC1), a transcriptional cofactor, has been
found to play important roles in regulating regulatory T cells, CD8+ T cells, and antitumor …

Purpose Schistosoma japonicum-infected IL-33 and ST2 gene deficiency (IL-33−/− and
ST2−/−, respectively) mice were used to explore the role of the IL-33/ST2 axis in liver …

Autophagy is a conserved process for self-degradation and provides cells with a rescue
mechanism to respond to circumstances such as stress and starvation. The role of …

Multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE) are
demyelinating neuroinflammatory diseases identified by the accumulation and aggregation …