Mesenchymal stem/stromal cell senescence: hallmarks, mechanisms, and combating strategies

Z Weng, Y Wang, T Ouchi, H Liu, X Qiao… - Stem Cells …, 2022 - academic.oup.com
Aging is a multifaceted and complicated process, manifested by a decline of normal
physiological functions across tissues and organs, leading to overt frailty, mortality, and …

Mitochondria‐targeted nanoparticles in treatment of neurodegenerative diseases

Y Zhang, H Yang, D Wei, X Zhang, J Wang, X Wu… - …, 2021 - Wiley Online Library
Neurodegenerative diseases (NDs) are a class of heterogeneous diseases that includes
Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral …

Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway

R Shen, K Yang, X Cheng, C Guo, X Xing, H Sun… - Environmental …, 2022 - Elsevier
The environmental pollution from microplastics has caused concern from the whole society
due to its harm to organisms. However, the effect of microplastics on liver damage and …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Cadmium induced BEAS-2B cells apoptosis and mitochondria damage via MAPK signaling pathway

X Cao, M Fu, R Bi, X Zheng, B Fu, S Tian, C Liu, Q Li… - Chemosphere, 2021 - Elsevier
Cadmium, a heavy metal pollutant in industrial production, is found in air, water and soil,
which is harmful to human health and can lead to diseases, such as asthma, lung cancer …

Mitochondria as an important target of metformin: The mechanism of action, toxic and side effects, and new therapeutic applications

J Feng, X Wang, X Ye, I Ares, B Lopez-Torres… - Pharmacological …, 2022 - Elsevier
Metformin is the oldest and most commonly used first-line antidiabetic drug because of its
good clinical efficacy, high safety, low cost and easy access. At the same time, in recent …

Mitochondrial dysfunction as a driver of NLRP3 inflammasome activation and its modulation through mitophagy for potential therapeutics

SR Mishra, KK Mahapatra, BP Behera, S Patra… - … International Journal of …, 2021 - Elsevier
The NLR family pyrin domain containing 3 (NLRP3) inflammasome is responsible for the
sensation of various pathogenic and non-pathogenic damage signals and has a vital role in …

Antioxidant Effects of Schisandra chinensis Fruits and Their Active Constituents

DM Kopustinskiene, J Bernatoniene - Antioxidants, 2021 - mdpi.com
Schisandra chinensis Turcz.(Baill.) fruits, their extracts, and bioactive compounds are used
in alternative medicine as adaptogens and ergogens protecting against numerous …

Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the SIRT1/PINK1/mitophagy axis

T Liu, Q Yang, X Zhang, R Qin, W Shan, H Zhang… - Life Sciences, 2020 - Elsevier
Emerging evidence implicates accelerated renal tubular epithelial cell (RTEC) senescence
in renal fibrosis progression. Mitophagy protects against kidney injury. However, the …

MFN1-dependent alteration of mitochondrial dynamics drives hepatocellular carcinoma metastasis by glucose metabolic reprogramming

Z Zhang, TE Li, M Chen, D Xu, Y Zhu, BY Hu… - British journal of …, 2020 - nature.com
Background Mitochondrial dynamics plays an important role in tumour progression.
However, how these dynamics integrate tumour metabolism in hepatocellular carcinoma …