Metabolomics in cancer research and emerging applications in clinical oncology
Cancer has myriad effects on metabolism that include both rewiring of intracellular
metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor …
metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor …
Biomedicine meets Fenton chemistry
Since the first connection between Fenton chemistry and biomedicine, numerous studies
have been presented in this field. Comprehensive presentation of the guidance from Fenton …
have been presented in this field. Comprehensive presentation of the guidance from Fenton …
An enzyme‐engineered nonporous copper (I) coordination polymer nanoplatform for cuproptosis‐based synergistic cancer therapy
Y Xu, SY Liu, L Zeng, H Ma, Y Zhang… - Advanced …, 2022 - Wiley Online Library
Cuproptosis, a newly identified form of regulated cell death that is copper‐dependent, offers
great opportunities for exploring the use of copper‐based nanomaterials inducing …
great opportunities for exploring the use of copper‐based nanomaterials inducing …
A polymeric hydrogel to eliminate programmed death-ligand 1 for enhanced tumor radio-immunotherapy
Programmed death-ligand 1 (PD-L1) is a specialized shield on tumor cells that evades the
immune system. Even inhibited by PD-L1 antibodies, a cycling process constantly transports …
immune system. Even inhibited by PD-L1 antibodies, a cycling process constantly transports …
Role of LDH in tumor glycolysis: regulation of LDHA by small molecules for cancer therapeutics
D Sharma, M Singh, R Rani - Seminars in cancer biology, 2022 - Elsevier
Lactate dehydrogenase (LDH) is one of the crucial enzymes in aerobic glycolysis, catalyzing
the last step of glycolysis, ie. the conversion of pyruvate to lactate. Most cancer cells are …
the last step of glycolysis, ie. the conversion of pyruvate to lactate. Most cancer cells are …
Chemical design of activatable photoacoustic probes for precise biomedical applications
Y Liu, L Teng, B Yin, H Meng, X Yin, S Huan… - Chemical …, 2022 - ACS Publications
Photoacoustic (PA) imaging technology, a three-dimensional hybrid imaging modality that
integrates the advantage of optical and acoustic imaging, has great application prospects in …
integrates the advantage of optical and acoustic imaging, has great application prospects in …
Metabolites and the tumour microenvironment: from cellular mechanisms to systemic metabolism
I Elia, MC Haigis - Nature metabolism, 2021 - nature.com
Metabolic transformation is a hallmark of cancer and a critical target for cancer therapy.
Cancer metabolism and behaviour are regulated by cell-intrinsic factors as well as …
Cancer metabolism and behaviour are regulated by cell-intrinsic factors as well as …
Signaling pathways and intervention therapies in sepsis
Y Zhang, B Ning - Signal Transduction and Targeted Therapy, 2021 - nature.com
Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …
systemic inflammatory and immune response to infection. Over decades, advanced …
The molecular biology of pancreatic adenocarcinoma: translational challenges and clinical perspectives
S Wang, Y Zheng, F Yang, L Zhu, XQ Zhu… - Signal transduction and …, 2021 - nature.com
Pancreatic cancer is an increasingly common cause of cancer mortality with a tight
correspondence between disease mortality and incidence. Furthermore, it is usually …
correspondence between disease mortality and incidence. Furthermore, it is usually …
Lactate dehydrogenase levels predict coronavirus disease 2019 (COVID-19) severity and mortality: A pooled analysis
BM Henry, G Aggarwal, J Wong, S Benoit… - The American journal of …, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) infection has now reached a pandemic
state, affecting more than a million patients worldwide. Predictors of disease outcomes in …
state, affecting more than a million patients worldwide. Predictors of disease outcomes in …