Furosemide is the diuretic of choice for the treatment of hypertension in chronic kidney
disease but the adaptative changes in the distal nephron may decrease its efficacy …

The effect of the thiazide diuretic, bemetizide, on the excretion of Na+, K+, Cl−, Ca 2+, and
Mg 2+ in relation to the glomerular filtration rate (GFR) was studied in 17 subjects whose …

Thiazide diuretics have been in existence for more than 3 decades. They are
benzothiadiazines or analogs and derivatives of the carbonic anhydrase–inhibiting …

The organic mercurials dominated the field of diuretics for many years but were far from
ideal since they required parenteral administration, caused metabolic acidosis that limited …

Elsewhere in this text considerable attention has been focused on the complex
interrelationship of systemic hypertension with kidney disease. Renal parenchymal and …

The sections in this article are:

1. Changes in extracellular water, plasma volume, blood urea and glomerular filtration rate
were recorded over intervals of up to 28 days in ten patients requiring diuretic therapy, eight …