Suicide and self-harm

D Knipe, P Padmanathan, G Newton-Howes, LF Chan… - The Lancet, 2022 - thelancet.com
Suicide and self-harm are major health and societal issues worldwide, but the greatest
burden of both behaviours occurs in low-income and middle-income countries. Although …

Suicide and suicide risk

G Turecki, DA Brent, D Gunnell, RC O'Connor… - Nature reviews Disease …, 2019 - nature.com
Although recent years have seen large decreases in the overall global rate of suicide
fatalities, this trend is not reflected everywhere. Suicide and suicidal behaviour continue to …

The genecards suite

M Safran, N Rosen, M Twik, R BarShir, TI Stein… - Practical guide to life …, 2021 - Springer
The GeneCards® database of human genes was launched in 1997 and has expanded
since then to encompass gene-centric, disease-centric, and pathway-centric entities and …

[HTML][HTML] Understanding the complex of suicide in depression: from research to clinics

L Orsolini, R Latini, M Pompili, G Serafini… - Psychiatry …, 2020 - ncbi.nlm.nih.gov
Objective Amongst psychiatric disorders, major depressive disorder (MDD) is the most
prevalent, by affecting approximately 15–17% of the population and showing a high suicide …

Gut microbiota and psychiatric disorders: a two-sample Mendelian randomization study

JJ Ni, Q Xu, SS Yan, BX Han, H Zhang, XT Wei… - Frontiers in …, 2022 - frontiersin.org
Evidence supports the observational associations of gut microbiota with a variety of
psychiatric disorders, but the causal nature of such associations remains obscure. Aiming to …

[HTML][HTML] Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors

N Mullins, JE Kang, AI Campos, JRI Coleman… - Biological …, 2022 - Elsevier
Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts,
which occur far more frequently, are a major source of disability and social and economic …

GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores

N Mullins, TB Bigdeli, AD Børglum… - American journal of …, 2019 - Am Psychiatric Assoc
Objective: More than 90% of people who attempt suicide have a psychiatric diagnosis;
however, twin and family studies suggest that the genetic etiology of suicide attempt is …

[HTML][HTML] A brain-centric model of suicidal behavior

JJ Mann, MM Rizk - American journal of psychiatry, 2020 - Am Psychiatric Assoc
The suicide death toll is alarmingly high, outnumbering deaths from war and homicide
worldwide (1). Many factors contribute to suicide death, making it difficult to prevent because …

Genome-wide association study meta-analysis of suicide death and suicidal behavior

QS Li, AA Shabalin, E DiBlasi, S Gopal… - Molecular …, 2023 - nature.com
Suicide is a worldwide health crisis. We aimed to identify genetic risk variants associated
with suicide death and suicidal behavior. Meta-analysis for suicide death was performed …

Associations of cigarette smoking with psychiatric disorders: evidence from a two-sample Mendelian randomization study

S Yuan, H Yao, SC Larsson - Scientific Reports, 2020 - nature.com
We conducted a two-sample Mendelian randomization study to determine the association of
smoking initiation with seven psychiatric disorders. We used 353 independent single …