Enhancing nervous system recovery through neurobiologics, neural interface training, and neurorehabilitation

MO Krucoff, S Rahimpour, MW Slutzky… - Frontiers in …, 2016 - frontiersin.org
After an initial period of recovery, human neurological injury has long been thought to be
static. In order to improve quality of life for those suffering from stroke, spinal cord injury, or …

Rethinking brain-wide interactions through multi-region 'network of networks' models

MG Perich, K Rajan - Current opinion in neurobiology, 2020 - Elsevier
Highlights•Brains can be viewed as a composition of anatomically distinct modules called
regions.•Brain regions interact in complex ways to form a 'network of networks'.•Untangling …

Deep neural networks rival the representation of primate IT cortex for core visual object recognition

CF Cadieu, H Hong, DLK Yamins, N Pinto… - PLoS computational …, 2014 - journals.plos.org
The primate visual system achieves remarkable visual object recognition performance even
in brief presentations, and under changes to object exemplar, geometric transformations …

Preparatory activity and the expansive null-space

MM Churchland, KV Shenoy - Nature Reviews Neuroscience, 2024 - nature.com
The study of the cortical control of movement experienced a conceptual shift over recent
decades, as the basic currency of understanding shifted from single-neuron tuning towards …

Is neuroimaging measuring information in the brain?

L de-Wit, D Alexander, V Ekroll… - Psychonomic bulletin & …, 2016 - Springer
Psychology moved beyond the stimulus response mapping of behaviorism by adopting an
information processing framework. This shift from behavioral to cognitive science was partly …

Different population dynamics in the supplementary motor area and motor cortex during reaching

AH Lara, JP Cunningham, MM Churchland - Nature communications, 2018 - nature.com
Neural populations perform computations through their collective activity. Different
computations likely require different population-level dynamics. We leverage this …

Analysis of neuronal spike trains, deconstructed

J Aljadeff, BJ Lansdell, AL Fairhall, D Kleinfeld - Neuron, 2016 - cell.com
As information flows through the brain, neuronal firing progresses from encoding the world
as sensed by the animal to driving the motor output of subsequent behavior. One of the more …

Inferring brain-wide interactions using data-constrained recurrent neural network models

MG Perich, C Arlt, S Soares, ME Young, CP Mosher… - BioRxiv, 2020 - biorxiv.org
Behavior arises from the coordinated activity of numerous anatomically and functionally
distinct brain regions. Modern experimental tools allow unprecedented access to large …

Maintained avalanche dynamics during task-induced changes of neuronal activity in nonhuman primates

S Yu, TL Ribeiro, C Meisel, S Chou, A Mitz, R Saunders… - Elife, 2017 - elifesciences.org
Sensory events, cognitive processing and motor actions correlate with transient changes in
neuronal activity. In cortex, these transients form widespread spatiotemporal patterns with …

Successful reconstruction of a physiological circuit with known connectivity from spiking activity alone

F Gerhard, T Kispersky, GJ Gutierrez… - PLoS computational …, 2013 - journals.plos.org
Identifying the structure and dynamics of synaptic interactions between neurons is the first
step to understanding neural network dynamics. The presence of synaptic connections is …