Diabetic sensorimotor peripheral neuropathy (DSPN) is a serious complication of diabetes
mellitus and is associated with increased mortality, lower-limb amputations and distressing …

Diabetic peripheral neuropathy (DPN) occurs in up to half of individuals with type 1 or type 2
diabetes. DPN results from the distal-to-proximal loss of peripheral nerve function, leading to …

Objective The objective of this clinical practice guideline is to provide updated and new
evidence-based recommendations for the comprehensive care of persons with diabetes …

Diabetic neuropathies are the most common chronic complications of diabetes, with an
estimated lifetime prevalence exceeding 50% in people with diabetes. Among various forms …

Diabetes prevalence continues to climb with the aging population. Type 2 diabetes (T2D),
which constitutes most cases, is metabolically acquired. Diabetic peripheral neuropathy …

The pathogenic mechanisms underlying distal symmetric polyneuropathy (DSPN), a
common neuropathy in patients with diabetes mellitus (DM), are not fully understood. Here …

Background Implanted spinal neuromodulation (SNMD) techniques are used in the
treatment of refractory chronic pain. They involve the implantation of electrodes around the …

Background Treatment response to spinal cord stimulation (SCS) is focused on the
magnitude of effects on pain intensity. However, chronic pain is a multidimensional condition …

Painful diabetic peripheral neuropathy (PDPN) is present in nearly a quarter of people with
diabetes. It is estimated to affect over 100 million people worldwide. PDPN is associated …

Objective To evaluate high-frequency (10-kHz) spinal cord stimulation (SCS) treatment in
refractory painful diabetic neuropathy. Patients and Methods A prospective, multicenter …