Large cell neuroendocrine carcinoma of the lung: current understanding and challenges

E Andrini, PV Marchese, D De Biase… - Journal of Clinical …, 2022 - mdpi.com
Large cell neuroendocrine carcinoma of the lung (LCNEC) is a rare and highly aggressive
type of lung cancer, with a complex biology that shares similarities with both small-cell lung …

Updates on lung neuroendocrine neoplasm classification

G Vocino Trucco, L Righi, M Volante… - Histopathology, 2024 - Wiley Online Library
Lung neuroendocrine neoplasms (NENs) are a heterogeneous group of pulmonary
neoplasms showing different morphological patterns and clinical and biological …

Spotlight on small-cell lung cancer and other lung neuroendocrine neoplasms

L Fernandez-Cuesta, A Sexton-Oates… - American Society of …, 2023 - ascopubs.org
Lung neuroendocrine neoplasms (NENs) encompass a spectrum of neoplasms that are
subdivided into the well-differentiated neuroendocrine tumors comprising the low-and …

[HTML][HTML] Cellular senescence in non-small cell lung cancer

H Zhu, J Sun, C Zhang, P Li, C Tan, M Yang… - Frontiers in Bioscience …, 2023 - imrpress.com
Lung cancer has the highest mortality rate amongst all malignancies worldwide, and is the
second-highest incidence of cancer in women. Non-small cell lung cancer (NSCLC) is …

Pulmonary large cell neuroendocrine carcinoma (LCNEC): a population-based study addressing recent molecular-genetic advances and emerging therapeutic …

J Khan, AQK Yasinzai, S Matosz, M Khan… - Clinical and …, 2023 - Springer
Background Large cell neuroendocrine carcinoma (LCNEC) of the lung is a rare, aggressive
cancer most commonly found in the lungs but not exclusively, with a worse prognosis than …

Case report: a pregnant woman diagnosed as ALK-rearrangement lung large cell neuroendocrine cancer with brain metastasis

Z Fu, G Zhu, L Wang, S Hu, L Cheng, F Liu - Frontiers in Oncology, 2022 - frontiersin.org
Concomitant malignant tumors and pregnancy present many difficult questions to both
clinicians and patients. Due to no specific guidelines, each aspect of clinical management …

Pulmonary neuroendocrine neoplasms overexpressing epithelial-mesenchymal transition mechanical barriers genes lack immune-suppressive response and present …

TG Prieto, CM Baldavira, J Machado-Rugolo… - Frontiers in …, 2021 - frontiersin.org
Typical carcinoids (TC), atypical carcinoids (AC), large cell neuroendocrine carcinomas
(LCNEC), and small cell lung carcinomas (SCLC) encompass a bimodal spectrum of …

BRAF V600E-mutated large cell neuroendocrine carcinoma responding to targeted therapy: a case report and review of the literature

G Ricco, R Seminerio, E Andrini, D Malvi… - Anti-Cancer …, 2023 - journals.lww.com
Large cell neuroendocrine carcinoma (LCNEC) is a rare and aggressive high-grade
neuroendocrine tumor, commonly arising in the lung or in the gastrointestinal tract, with a …

The Unmet Diagnostic and Treatment Needs in Large Cell Neuroendocrine Carcinoma of the Lung

C Buium, S Negru, DN Ionescu, M Dediu - Current Oncology, 2023 - mdpi.com
Large cell neuroendocrine carcinoma of the lung (LCNEC) is currently classified as a rare
lung cancer subtype, but given the high incidence of lung cancer, the overall number of …

Spread Through Air Spaces in Stage I Pulmonary Large Cell Neuroendocrine Carcinoma

S Wan, Z Shen, S Hu, L Zhang, H Yu, Y Chen… - The Annals of Thoracic …, 2024 - Elsevier
Background Pulmonary large cell neuroendocrine carcinoma (LCNEC) represents an
exceptionally aggressive and infrequent variant within the realm of non-small cell lung …