The hyperdirect pathway (HDP) represents the main glutamatergic input to the subthalamic
nucleus (STN), through which the motor and prefrontal cerebral cortex can modulate basal …

Brain cell structure is a key determinant of neural function that is frequently altered in
neurobiological disorders. Following the global loss of blood flow to the brain that initiates …

Stress response is a cellular widespread mechanism encoded by a common protein
program composed by multiple cellular factors that converge in a defense reaction to protect …

Severe stress exposure causes the loss of dendritic spines on cortical pyramidal neurons
and induces psychiatric-like symptoms in rodent models. These effects are strongest …

In the present study, we conducted a scoping review to provide an overview of the existing
literature on the carbocyanine dye DiI, in human neuroanatomical tract tracing. The PubMed …

Excitatory synapse formation begins in mid‐fetal gestation. However, due to our inability to
image fetal synaptogenesis, the initial formation of synapses remains understudied. The …

Environmental changes cause stress, Reactive Oxygen Species and unfolded protein
accumulation which hamper synaptic activity and trigger cell death. Heat shock proteins …

Many experiments suggest that long-term information associated with neuronal memory
resides collectively in dendritic spines. However, spines can have a limited size due to …

A tiny detail visible on certain neurons at the limit of resolution in light microscopy went in
130 years of neuroscience research through a dazzling career from suspicious staining …

Background Suicide is a manner of death resulting from complex environmental and genetic
risks that affect millions of people globally. Both structural and functional studies identified …