In recent decades, collagen is one of the most versatile biomaterials used in biomedical
applications, mostly due to its biomimetic and structural composition in the extracellular …

In recent years, porous bioactive glass micro/nanospheres (PBGSs) have emerged as
attractive biomaterials in various biomedical applications where such engineered particles …

Critical-sized bone defect repair in patients with diabetes mellitus remains a challenge in
clinical treatment because of dysfunction of macrophage polarization and the inflammatory …

Regenerating defective bone in patients with diabetes mellitus remains a significant
challenge due to high blood glucose level and oxidative stress. Here we aim to tackle this …

Severe injuries and diseases of bone tissue caused by congenital disorder, extrinsic trauma,
infection, and osteosarcoma resection face significant challenges for complete recovery. The …

Bone is a hard-connective tissue composed of matrix, cells and bioactive factors with a
hierarchical structure, where the matrix is mainly composed of type I collagen and …

Therapeutic options are quite limited in clinics for the successful repair of
infected/degenerated tissues. Although the prevalent treatment is the complete removal of …

Porous nano-scaffolds provide for better opportunities to restore, maintain, and improve
functions of damaged tissues and organs by facilitating tissue regeneration. Various …

Biomedical cements are considered promising injectable materials for bone repair and
regeneration. Calcium phosphate composition sized with tens of micrometers is currently …

The efficacy of stem cell-based bone tissue engineering has been hampered by cell death
and limited fate control. A smart cell culture system with the capability of sequentially …