The mechanobiology of brain function

WJ Tyler - Nature Reviews Neuroscience, 2012 - nature.com
All cells are influenced by mechanical forces. In the brain, force-generating and load-
bearing proteins twist, turn, ratchet, flex, compress, expand and bend to mediate neuronal …

Recent advances in microfluidic techniques for single-cell biophysical characterization

Y Zheng, J Nguyen, Y Wei, Y Sun - Lab on a Chip, 2013 - pubs.rsc.org
Biophysical (mechanical and electrical) properties of living cells have been proven to play
important roles in the regulation of various biological activities at the molecular and cellular …

Review on cell mechanics: experimental and modeling approaches

ML Rodriguez, PJ McGarry… - Applied …, 2013 - asmedigitalcollection.asme.org
The interplay between the mechanical properties of cells and the forces that they produce
internally or that are externally applied to them play an important role in maintaining the …

Recent advances in the use of microfluidic technologies for single cell analysis

TW Murphy, Q Zhang, LB Naler, S Ma, C Lu - Analyst, 2018 - pubs.rsc.org
The inherent heterogeneity in cell populations has become of great interest and importance
as analytical techniques have improved over the past decades. With the advent of …

A mechanical biomarker of cell state in medicine

D Di Carlo - Journal of laboratory automation, 2012 - journals.sagepub.com
The mechanical properties of cells have been shown to be useful markers of cell state by the
biophysics community. Here, I highlight clinical and research problems that this label-free …

Imaging single cells in a beam of live cyanobacteria with an X-ray laser

G Van Der Schot, M Svenda, FRNC Maia… - Nature …, 2015 - nature.com
There exists a conspicuous gap of knowledge about the organization of life at mesoscopic
levels. Ultra-fast coherent diffractive imaging with X-ray free-electron lasers can probe …

Classification of cell types using a microfluidic device for mechanical and electrical measurement on single cells

J Chen, Y Zheng, Q Tan, E Shojaei-Baghini, YL Zhang… - Lab on a Chip, 2011 - pubs.rsc.org
This paper presents a microfluidic system for cell type classification using mechanical and
electrical measurements on single cells. Cells are aspirated continuously through a …

Testis on a chip—a microfluidic three-dimensional culture system for the development of spermatogenesis in-vitro

A AbuMadighem, S Shuchat, E Lunenfeld… - …, 2022 - iopscience.iop.org
This research presents a novel testis-on-a-chip (ToC) platform. Testicular cells are
enzymatically isolated from the seminiferous tubules of sexually immature mice, seeded in a …

Microfluidic deformability cytometry: A review

Y Chen, K Guo, L Jiang, S Zhu, Z Ni, N Xiang - Talanta, 2023 - Elsevier
Cell deformability plays an important role in cellular processes and functions, including cell
growth and differentiation, as well as cell transfer and cell cycle. Measuring deformability at …

Mesenchymal stem cell mechanobiology and emerging experimental platforms

L MacQueen, Y Sun… - Journal of the Royal …, 2013 - royalsocietypublishing.org
Experimental control over progenitor cell lineage specification can be achieved by
modulating properties of the cell's microenvironment. These include physical properties of …