Programmed cell death (PCD) plays a fundamental role in animal development and tissue
homeostasis. Abnormal regulation of this process is associated with a wide variety of human …

Human pluripotent stem cells (hPSCs), including embryonic and induced pluripotent stem
cells, constitute an extremely attractive tool for cell therapy. However, flexible platforms for …

Abstract The International Stem Cell Initiative analyzed 125 human embryonic stem (ES) cell
lines and 11 induced pluripotent stem (iPS) cell lines, from 38 laboratories worldwide, for …

In the 20 years since human embryonic stem cells, and subsequently induced pluripotent
stem cells, were first described, it has become apparent that during long-term culture these …

The survival, proliferation, self-renewal and differentiation of human pluripotent stem cells
(hPSCs, including human embryonic stem cells and human induced pluripotent stem cells) …

Genome editing of human induced pluripotent stem cells (iPSCs) is instrumental for
functional genomics, disease modeling, and regenerative medicine. However, low editing …

RNA-binding proteins (RBPs) are increasingly identified as post-transcriptional drivers of
cancer progression. The RBP LARP1 is an mRNA stability regulator, and elevated …

Apoptosis, as a programmed cell death (PCD) is essential for normal cell mechanism. The
word “Apoptosis” derives from Greek language “απόπτωσις” and means trees shedding their …

Human pluripotent stem cells (hPSCs) require precise control of post-transcriptional RNA
networks to maintain proliferation and survival. Using enhanced UV crosslinking and …

Cardiotoxicity remains the number one reason for drug withdrawal from the market, and
Food and Drug Administration issued black box warnings, thus demonstrating the need for …