Candida glabrata: Pathogenicity and Resistance Mechanisms for Adaptation and Survival
Candida glabrata is a yeast of increasing medical relevance, particularly in critically ill
patients. It is the second most isolated Candida species associated with invasive candidiasis …
patients. It is the second most isolated Candida species associated with invasive candidiasis …
Candida glabrata: A Lot More Than Meets the Eye
Candida glabrata is an opportunistic human fungal pathogen that causes superficial
mucosal and life-threatening bloodstream infections in individuals with a compromised …
mucosal and life-threatening bloodstream infections in individuals with a compromised …
The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus
T Furukawa, N Van Rhijn, M Fraczek, F Gsaller… - Nature …, 2020 - nature.com
The frequency of antifungal resistance, particularly to the azole class of ergosterol
biosynthetic inhibitors, is a growing global health problem. Survival rates for those infected …
biosynthetic inhibitors, is a growing global health problem. Survival rates for those infected …
Candida glabrata Antifungal Resistance and Virulence Factors, a Perfect Pathogenic Combination
MG Frías-De-León, R Hernández-Castro… - Pharmaceutics, 2021 - mdpi.com
In recent years, a progressive increase in the incidence of invasive fungal infections (IFIs)
caused by Candida glabrata has been observed. The objective of this literature review was …
caused by Candida glabrata has been observed. The objective of this literature review was …
Novel nanocarrier of miconazole based on chitosan-coated iron oxide nanoparticles as a nanotherapy to fight Candida biofilms
Overexposure of microorganisms to conventional drugs has led to resistant species that
require new treatment strategies. This study prepared and characterized a nanocarrier of …
require new treatment strategies. This study prepared and characterized a nanocarrier of …
The Set1 histone H3K4 methyltransferase contributes to azole susceptibility in a species-specific manner by differentially altering the expression of drug efflux pumps …
Fungal infections are a major health concern because of limited antifungal drugs and
development of drug resistance. Candida can develop azole drug resistance by …
development of drug resistance. Candida can develop azole drug resistance by …
Caspofungin-resistance in Candida auris is cell wall-dependent phenotype and potential prevention by zinc oxide nanoparticles
Candida auris is an emergent nosocomial multi-drug-resistant yeast that represents a global
health threat. Recently, C. auris clinical isolates with caspofungin resistance were identified …
health threat. Recently, C. auris clinical isolates with caspofungin resistance were identified …
Erg6p is essential for antifungal drug resistance, plasma membrane properties and cell wall integrity in Candida glabrata
D Elias, N Toth Hervay, J Jacko… - FEMS Yeast …, 2022 - academic.oup.com
ERG6 gene encodes C-24 methyltransferase, one of the specific enzymes that differ in
mammalian and yeast sterol biosynthesis. To explore the function of Cg Erg6p in the yeast …
mammalian and yeast sterol biosynthesis. To explore the function of Cg Erg6p in the yeast …
[HTML][HTML] Human β defensins-1, an antimicrobial peptide, kills Candida glabrata by generating oxidative stress and arresting the cell cycle in G0/G1 phase
Candida glabrata is the most frequently isolated non-albicans Candida species in clinical
samples and is known to develop resistance to commonly used antifungal drugs. Human β …
samples and is known to develop resistance to commonly used antifungal drugs. Human β …
Population genomic analyses reveal high diversity, recombination and nosocomial transmission among Candida glabrata (Nakaseomyces glabrata) isolates causing …
Candida glabrata is a commensal yeast of the gastrointestinal tract and skin of humans.
However, it causes opportunistic infections in immunocompromised patients, and is the …
However, it causes opportunistic infections in immunocompromised patients, and is the …