Different neuroplastic processes can occur along the nociceptive pathways and may be
important in the transition from acute to chronic pain and for diagnosis and development of …

Background Over the past 2 decades, the use of intravenous ketamine infusions as a
treatment for chronic pain has increased dramatically, with wide variation in patient …

Postamputation pain (PAP) is highly prevalent after limb amputation but remains an
extremely challenging pain condition to treat. A large part of its intractability stems from the …

Peripheral neuropathic pain is produced by multiple etiological factors that initiate a number
of diverse mechanisms operating at different sites and at different times and expressed both …

Pain is a personal, subjective experience influenced by cultural learning, the meaning of the
situation, attention, and other psychological variables. 77 Pain processes do not begin with …

Phantom-limb pain is a common sequela of amputation, occurring in up to 80% of people
who undergo the procedure. It must be differentiated from non-painful phantom phenomena …

Quantification of the human painful sensory experience is an essential step in the translation
of knowledge from animal nociception to human pain. Translational models for assessment …

Background This is an updated version of the original Cochrane review published in Issue
12, 2011. Phantom limb pain (PLP) is pain that arises in the missing limb after amputation …

Wind-up is a frequency-dependent increase in the excitability of spinal cord neurones,
evoked by electrical stimulation of afferent C-fibres. Although it has been studied over the …

Methods: This review aims to provide an interdisciplinary overview of recent evidence-based
and clinical knowledge. Results: The scientific evidence for best practice is weak and …