Establishing equivalent aerobic exercise parameters between early-stage Parkinson's disease and Pink1 knockout rats

MF Salvatore, I Soto, EA Kasanga… - Journal of …, 2022 - content.iospress.com
Background: Rodent Parkinson's disease (PD) models are valuable to interrogate
neurobiological mechanisms of exercise that mitigate motor impairment. Translating these …

Moderate intensity aerobic exercise alleviates motor deficits in 6-OHDA lesioned rats and reduces serum levels of biomarkers of Parkinson's disease severity without …

EA Kasanga, I Soto, A Centner, R McManus… - Experimental …, 2024 - Elsevier
Alleviation of motor impairment by aerobic exercise (AE) in Parkinson's disease (PD)
patients points to activation of neurobiological mechanisms that may be targetable by …

Modulation of nigral dopamine signaling mitigates parkinsonian signs of aging: evidence from intervention with calorie restriction or inhibition of dopamine uptake

MF Salvatore, EA Kasanga, DP Kelley, KE Venable… - GeroScience, 2023 - Springer
Identifying neurobiological mechanisms of aging-related parkinsonism, and lifestyle
interventions that mitigate them, remain critical knowledge gaps. No aging study, from rodent …

Moderate intensity aerobic exercise in 6-OHDA-lesioned rats alleviates established motor deficits and reduces neurofilament light and glial fibrillary acidic protein …

EA Kasanga, I Soto, A Centner, R McManus… - bioRxiv, 2023 - biorxiv.org
Background: Alleviation of motor impairment by aerobic exercise (AE) in Parkinsons disease
(PD) points to a CNS response that could be targeted by therapeutic approaches, but …