Technetium-99m based small molecule radiopharmaceuticals and radiotracers targeting inflammation and infection

T Kniess, M Laube, F Wüst, J Pietzsch - Dalton transactions, 2017 - pubs.rsc.org
In nuclear medicine, the detection of inflamed and infected lesions is of growing interest.
Extensive efforts have been made to develop radiopharmaceuticals specific for inflammation …

Radioiodination, diagnostic nuclear imaging and bioevaluation of olmesartan as a tracer for cardiac imaging

HM Sanad, AA Ibrahim - Radiochimica Acta, 2018 - degruyter.com
The present work has been oriented to prepare radioiodinated olmesartan for a potential
cardiac imaging. Olmesartan has been labeled using 125 I or 131 I with N …

Preparation, biodistribution and dosimetry study of Tc-99m labeled N-doped graphene quantum dot nanoparticles as a multimodular radiolabeling agent

E Gharepapagh, A Fakhari, T Firuzyar… - New Journal of …, 2021 - pubs.rsc.org
A new Tc-99m N-doped graphene quantum dot 99mTc-(N-GQD) moiety was developed as a
radiolabeling agent for molecules lacking chelation or water solubility of ligands …

Radiosynthesis, Preparation, and Biological Evaluation of [99MTC]Tricarbonyl Pantoprazole for Stomach Ulcer Detection in Mice

MH Sanad, HM Eyssa, FA Marzook… - Pharmaceutical …, 2024 - Springer
In this work, the complex of [99mTc] tricarbonyl pantoprazole was labeled utilizing a [99mTc]
tricarbonyl core. Many optimum parameters have been used such as substrate (200 μg), pH …