Saliva is of paramount importance for the maintenance of oral and general homeostasis.
Salivary hypofunction predispose patients to disorders such as dysgeusia, pain and burning …

Salivary gland (SG) dysfunction, due to radiotherapy, disease, or aging, is a clinical
manifestation that has the potential to cause severe oral and/or systemic diseases and …

The human salivary gland (SG) has an elegant architecture of epithelial acini, connecting
ductal branching structures, vascular and neuronal networks that together function to …

Saliva is key to the maintenance of oral homeostasis. However, several forms of salivary
gland (SG) disorders, followed by hyposalivation, often result in dental caries, oral infection …

The mammalian salivary gland develops as a highly branched structure designed to
produce and secrete saliva. This review will focus on research on mouse submandibular …

Permanent damage to the salivary glands and resulting hyposalivation and xerostomia have
a substantial impact on patient health, quality of life, and healthcare costs. Currently, patients …

Salivary gland (SG) dysfunction impairs the life quality of many patients, such as patients
with radiation therapy for head and neck cancer and patients with Sjögren's syndrome …

IL-1β, a pro-inflammatory cytokine, has been shown to contribute to radiation injury. Sirt1, an
NAD+-dependent class III protein deacetylase, plays an important role in the regulation of …

Objectives Cell-based therapy has been reported to repair or restore damaged salivary
gland (SG) tissue after irradiation. This study was aimed at determining whether systemic …

Stem cell–based regenerative therapy is a promising treatment for head and neck cancer
patients that suffer from chronic dry mouth (xerostomia) due to salivary gland injury from …