Current insights into epigenetics, noncoding RNA interactome and clinical pharmacokinetics of dietary polyphenols in cancer chemoprevention

D Shah, M Gandhi, A Kumar… - Critical reviews in …, 2023 - Taylor & Francis
Several studies have reported the health-beneficial effects of dietary phytochemicals,
namely polyphenols, to prevent various diseases, including cancer. Polyphenols, like (−) …

Sensing the scent of death: modulation of microRNAs by curcumin in gastrointestinal cancers

M Ashrafizadeh, A Zarrabi, M Hashemipour… - Pharmacological …, 2020 - Elsevier
Gastrointestinal (GI) cancers with a high incidence rate and adverse complications are
related to severe morbidity and mortality around the world. MicroRNAs (miRs) are potential …

Increased miR‐34c mediates synaptic deficits by targeting synaptotagmin 1 through ROS‐JNK‐p53 pathway in Alzheimer's disease

Z Shi, K Zhang, H Zhou, L Jiang, B Xie, R Wang… - Aging cell, 2020 - Wiley Online Library
Alzheimer's disease (AD) and cancer have inverse relationship in many aspects. Some
tumor suppressors, including miR‐34c, are decreased in cancer but increased in AD. The …

The epigenetic modulation of cancer and immune pathways in hepatitis B virus-associated hepatocellular carcinoma: the influence of HBx and miRNA dysregulation

K Sartorius, P An, C Winkler, A Chuturgoon… - Frontiers in …, 2021 - frontiersin.org
Hepatitis B virus (HBV)-associated hepatocellular carcinoma (HBV-HCC) pathogenesis is
fueled by persistent HBV infection that stealthily maintains a delicate balance between viral …

MicroRNA-34 family in cancers: role, mechanism, and therapeutic potential

J Fu, S Imani, MY Wu, RC Wu - Cancers, 2023 - mdpi.com
Simple Summary The dysregulation of the miR-34 family has been shown to play an
important role in tumorigenesis and cancer progression. In this review, we summarized the …

[HTML][HTML] Curcumin and its novel formulations for the treatment of hepatocellular carcinoma: new trends and future perspectives in cancer therapy

SM Meybodi, P Rezaei, N Faraji… - Journal of Functional …, 2023 - Elsevier
Hepatocellular carcinoma (HCC), as a common malignancy of the liver, is the second
leading cause of cancer-related death in the world and mostly occurs in patients with a …

A novel strategy for the diagnosis, prognosis, treatment, and chemoresistance of hepatocellular carcinoma: DNA methylation

A Liu, Q Wu, D Peng, I Ares, A Anadón… - Medicinal Research …, 2020 - Wiley Online Library
The cancer mortality rate of hepatocellular carcinoma (HCC) is the second highest in the
world and the therapeutic options are limited. The incidence of this deadly cancer is rising at …

miR‑148a, miR‑152 and miR‑200b promote prostate cancer metastasis by targeting DNMT1 and PTEN expression

V Gurbuz, S Sozen, CY Bilen… - Oncology …, 2021 - spandidos-publications.com
MicroRNAs (miRs) modulate the expression of target genes in the signal pathway on
transcriptome level. The present study investigated the 'epigenetic‑based miRNA (epi …

MicroRNA-34a/EGFR axis plays pivotal roles in lung tumorigenesis

YL Li, XM Liu, CY Zhang, JB Zhou, Y Shao, C Liang… - Oncogenesis, 2017 - nature.com
MicroRNAs (miRNAs) are vital in the regulation of tumor progression and invasion.
Dysregulation of miRNAs has been linked to the development of various types of human …

Non-coding RNAs underlying chemoresistance in gastric cancer

A Poursheikhani, Z Bahmanpour, E Razmara… - Cellular oncology, 2020 - Springer
Background Gastric cancer (GC) is a major health issue in the Western world. Current
clinical imperatives for this disease include the identification of more effective biomarkers to …