Peroxisome proliferator-activated receptors (PPARs) function as nuclear transcription factors
upon the binding of physiological or pharmacological ligands and heterodimerization with …

Signalling lipids are known to control a wide array of cellular processes, including cell
proliferation, apoptosis, migration, and energy metabolism. Fatty acids and their derivatives …

It is now widely accepted that insulin resistance and compensatory hyperinsulinemia are
associated to increased cancer incidence and mortality. Moreover, cancer development and …

System xc− is a sodium-independent electroneutral transporter, comprising a catalytic
subunit xCT (SLC7A11), which is involved in importing cystine. Certain cancers such as …

In this study, a reactive oxygen species (ROS)‐responsive hydrogel sensor (PD/MnO2
hydrogel) is developed that can efficiently detect senescent cells. Using immature murine …

Nerve growth factor receptor (NGFR), a member of kinase protein, is emerging as an
important target for Glioblastoma (GBM) treatment. Overexpression of NGFR is observed in …

Fenofibrate (FF) is a common lipid-lowering drug and a potent agonist of the peroxisome
proliferator-activated receptor alpha (PPARα). FF and several other agonists of PPARα have …

Cancer is a leading cause of death throughout the world, and cancer therapy remains a big
medical challenge in terms of both its therapeutic efficacy and safety. Therefore, to find out a …

Among metabolic rearrangements occurring in cancer cells, lipid metabolism alteration has
become a hallmark, aimed at sustaining accelerated proliferation. In particular, fatty acids …

Abstract Transmembrane-4-L-Six-Family-1 (TM4SF1) is a member of the L6 family and
functions as a signal transducer to regulate cell development, growth and motility. Here we …