Neutrophils in cancer carcinogenesis and metastasis

S Xiong, L Dong, L Cheng - Journal of hematology & oncology, 2021 - Springer
In recent years, neutrophils have attracted increasing attention because of their cancer-
promoting effects. An elevated neutrophil-to-lymphocyte ratio is considered a prognostic …

Neutrophils in cancer: heterogeneous and multifaceted

CC Hedrick, I Malanchi - Nature Reviews Immunology, 2022 - nature.com
Neutrophils are the most abundant myeloid cells in human blood and are emerging as
important regulators of cancer. However, their functional importance has often been …

Neutrophil diversity and plasticity in tumour progression and therapy

S Jaillon, A Ponzetta, D Di Mitri, A Santoni… - Nature Reviews …, 2020 - nature.com
Neutrophils play a key role in defence against infection and in the activation and regulation
of innate and adaptive immunity. In cancer, tumour-associated neutrophils (TANs) have …

[HTML][HTML] Tumor-associated neutrophils and neutrophil-targeted cancer therapies

H Que, Q Fu, T Lan, X Tian, X Wei - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Neutrophils are the frontline cells in response to microbial infections and are involved in a
range of inflammatory disorders in the body. In recent years, neutrophils have gained …

Intratumoral microbiota: roles in cancer initiation, development and therapeutic efficacy

L Yang, A Li, Y Wang, Y Zhang - Signal transduction and targeted …, 2023 - nature.com
Microorganisms, including bacteria, viruses, fungi, and other eukaryotes, play critical roles in
human health. An altered microbiome can be associated with complex diseases …

Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance

HN Bell, RJ Rebernick, J Goyert, R Singhal, M Kuljanin… - Cancer cell, 2022 - cell.com
Microbial dysbiosis is a colorectal cancer (CRC) hallmark and contributes to inflammation,
tumor growth, and therapy response. Gut microbes signal via metabolites, but how the …

[HTML][HTML] Gut microbiota modulation: a novel strategy for prevention and treatment of colorectal cancer

W Fong, Q Li, J Yu - Oncogene, 2020 - nature.com
Research about the role of gut microbiome in colorectal cancer (CRC) is a newly emerging
field of study. Gut microbiota modulation, with the aim to reverse established microbial …

Tumor-associated neutrophils in cancer: going pro

L Wu, S Saxena, M Awaji, RK Singh - Cancers, 2019 - mdpi.com
The progression of cancer is not only about the tumor cell itself, but also about other
involved players including cancer cell recruited immune cells, their released pro …

Effects of antibiotics upon the gut microbiome: a review of the literature

T Konstantinidis, C Tsigalou, A Karvelas… - Biomedicines, 2020 - mdpi.com
The human gastrointestinal tract carries a large number of microorganisms associated with
complex metabolic processes and interactions. Although antibiotic treatment is crucial for …

Microbiota in tumors: from understanding to application

Y Xie, F Xie, X Zhou, L Zhang, B Yang… - Advanced …, 2022 - Wiley Online Library
Microbes with complex functions have been found to be a potential component in tumor
microenvironments. Due to their low biomass and other obstacles, intratumor microbiota is …