Epigenetic reprogramming during somatic cell nuclear transfer: recent progress and future directions

X Wang, J Qu, J Li, H He, Z Liu, Y Huan - Frontiers in Genetics, 2020 - frontiersin.org
Somatic cell nuclear transfer (SCNT) has broad applications but is limited by low cloning
efficiency. In this review, we mainly focus on SCNT-mediated epigenetic reprogramming in …

Porcine germline genome engineering

L Yang, G Church, HY Zhao, L Huang… - Proceedings of the …, 2021 - National Acad Sciences
Germline editing, the process by which the genome of an individual is edited in such a way
that the change is heritable, has been applied to a wide variety of animals [DA Sorrell, AF …

Perspectives in Genome-Editing Techniques for Livestock

J Popova, V Bets, E Kozhevnikova - Animals, 2023 - mdpi.com
Simple Summary Genetically modified farm animals have been actively used in a number of
applications from testing gene functions to increasing production and economic value of …

CRISPR editing technology in biological and biomedical investigation

MK White, R Kaminski, WB Young… - Journal of cellular …, 2017 - Wiley Online Library
The CRISPR or clustered regularly interspaced short palindromic repeats system is currently
the most advanced approach to genome editing and is notable for providing an …

Livestock and risk group 4 pathogens: researching zoonotic threats to public health and agriculture in maximum containment

CE Lewis, B Pickering - ILAR journal, 2020 - academic.oup.com
Maximum-containment laboratories are a unique and essential component of the
bioeconomy of the United States. These facilities play a critical role in the national …

Genetic engineering of novel products of health significance: Recombinant DNA technology

M Akram, F Jabeen, M Daniyal, R Zainab… - Functional Foods and …, 2020 - Springer
Biotechnology involves the use of living organisms, their systems and processes in
manufacturing or service industries. Biotechnology has presented a contemporary medical …

Agricultural animals as biomedical models: occupational health and safety considerations

GL Edwards, MJ Azain, A Parks - ILAR journal, 2018 - academic.oup.com
The use of agricultural animals in biomedical research is increasing. Their overall size and
metabolic rate, organ size, longer gestation period, and other physiological similarities make …

Strategies for transfection of bovine mesenchymal stem cells with pBC1-anti-CD3 vector

FB Duarte, MM Brígido, EO Melo, SN Báo… - Animal …, 2022 - Taylor & Francis
Cells from different origins behave differently regarding the incorporation of exogenous DNA
and formation of transgenic cells. Milk production of recombinant antibody may benefit from …

[HTML][HTML] Эмбриологические аспекты создания новой гуманизированной трансгенной линии мышей с интегрированным геном человека HLA-A* 02: 01: 01: 01

ЕС Савченко, НС Огнева, НН Каркищенко - Биомедицина, 2022 - cyberleninka.ru
Накопление научных данных в области фармакогенетики требует создания
адекватных релевантных биомоделей, отражающих иммуногенетические особенности …

Achievements and perspectives in cloned and transgenic cattle production by nuclear transfer: influence of cell type, epigenetic status and new technology

AG Curcio, FF Bressan… - Animal Reproduction …, 2018 - animal-reproduction.org
Genetically modified cattle production is motivated by many factors, including recombinant
protein production for therapeutic purposes, disease models and animals presenting …