Role of free fatty acids in endothelial dysfunction

A Ghosh, L Gao, A Thakur, PM Siu, CWK Lai - Journal of biomedical …, 2017 - Springer
Plasma free fatty acids levels are increased in subjects with obesity and type 2 diabetes,
playing detrimental roles in the pathogenesis of atherosclerosis and cardiovascular …

The role of lipid metabolism in T lymphocyte differentiation and survival

D Howie, A Ten Bokum, AS Necula… - Frontiers in …, 2018 - frontiersin.org
The differentiation and effector functions of both the innate and adaptive immune system are
inextricably linked to cellular metabolism. The features of metabolism which affect both arms …

Anti-oxidant effect of gold nanoparticles restrains hyperglycemic conditions in diabetic mice

S BarathManiKanth, K Kalishwaralal, M Sriram… - Journal of …, 2010 - Springer
Background Oxidative stress is imperative for its morbidity towards diabetic complications,
where abnormal metabolic milieu as a result of hyperglycemia, leads to the onset of several …

Fatty acid–derived signals in plant defense

A Kachroo, P Kachroo - Annual review of phytopathology, 2009 - annualreviews.org
Fatty acids (FAs) consist of long hydrophobic, often unbranched chains of hydrocarbons,
with hydrophilic carboxylic acid groups at one end. They are an important source of reserve …

Fatty acids as modulators of the cellular production of reactive oxygen species

P Schönfeld, L Wojtczak - Free Radical Biology and Medicine, 2008 - Elsevier
Long-chain nonesterified (“free”) fatty acids (FFA) and some of their derivatives and
metabolites can modify intracellular production of reactive oxygen species (ROS), in …

Pro-oxidant natural products as anticancer agents

C Martin-Cordero, A Jose Leon-Gonzalez… - Current drug …, 2012 - ingentaconnect.com
Cancer cells produce high levels of reactive oxygen species (ROS) that lead to a state of
increased basal oxidative stress. Since this state of oxidative stress makes cancer cells …

Fatty acids, lipid mediators, and T-cell function

AJ de Jong, M Kloppenburg, REM Toes… - Frontiers in …, 2014 - frontiersin.org
Research toward the mechanisms underlying obesity-linked complications has intensified
during the last years. As a consequence, it has become clear that metabolism and immunity …

Untargeted LC–MS/MS-Based Metabolomic Profiling for the Edible and Medicinal Plant Salvia miltiorrhiza Under Different Levels of Cadmium Stress

J Yuan, R Liu, S Sheng, H Fu, X Wang - Frontiers in plant science, 2022 - frontiersin.org
Salvia miltiorrhiza, a medicinal and edible plant, has been extensively applied to treat
cardiovascular diseases and chronic hepatitis. Cadmium (Cd) affects the quality of S …

[HTML][HTML] Oral administration of oleic or linoleic acid accelerates the inflammatory phase of wound healing

HG Rodrigues, MAR Vinolo, J Magdalon… - Journal of Investigative …, 2012 - Elsevier
The effects of oral ingestion of oleic (OLA) and linoleic (LNA) acids on wound healing in rats
were investigated. LNA increased the influx of inflammatory cells, the concentration of …

Sterol and diacylglycerol acyltransferase deficiency triggers fatty acid-mediated cell death

J Garbarino, M Padamsee, L Wilcox, PM Oelkers… - Journal of Biological …, 2009 - ASBMB
Deletion of the acyltransferases responsible for triglyceride and steryl ester synthesis in
Saccharomyces cerevisiae serves as a genetic model of diseases where lipid overload is a …