Children and adolescents infected with severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are predominantly asymptomatic or have mild symptoms compared with the …

Abstract Purpose of Review Provide the most recent updates on the epidemiology,
pathogenesis, and treatment advances in Kawasaki disease. Recent Findings Treatment …

Background: Cardiac injury and myocarditis have been described in adults with coronavirus
disease 2019 (COVID-19). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Objective To provide guidance on the management of multisystem inflammatory syndrome
in children (MIS‐C), a condition characterized by fever, inflammation, and multiorgan …

Objective To provide guidance on the management of Multisystem Inflammatory Syndrome
in Children (MIS‐C), a condition characterized by fever, inflammation, and multiorgan …

Background Current data suggest that COVID-19 is less frequent in children, with a milder
course. However, over the past weeks, an increase in the number of children presenting to …

Abstract The interleukin (IL)-1 family member IL-1α is a ubiquitous and pivotal pro-
inflammatory cytokine. The IL-1α precursor is constitutively present in nearly all cell types in …

Objective To provide guidance on the management of Multisystem Inflammatory Syndrome
in Children (MIS‐C), a condition characterized by fever, inflammation, and multiorgan …

More than any other cytokine family, the 11 members of the IL-1 family are associated with
innate immune responses, which occur in acute inflammation and chronic inflammatory …

Interleukin-1 (IL-1) is the prototypical inflammatory cytokine: two distinct ligands (IL-1α and IL-
1β) bind the IL-1 type 1 receptor (IL-1R1) and induce a myriad of secondary inflammatory …