Self-replicating RNA viruses have been engineered as efficient expression vectors for
vaccine development for infectious diseases and cancers. Moreover, self-replicating RNA …

The Vero cell line is the most used continuous cell line in viral vaccine manufacturing. This
adherent cell culture platform requires the use of surfaces to support cell growth, typically …

Despite the human immunodeficiency virus (HIV) pandemic continuing worldwide for 40
years, no vaccine to combat the disease has been licenced for use in at risk populations …

In recent years, tattooing technology has shown promising results toward evaluating
vaccines in both animal models and humans. However, this technology has some limitations …

Recombinant technology-based vaccines have emerged as a highly effective way to prevent
a wide range of illnesses. The technology improved vaccine manufacturing, rendering it …

Viable cell density (VCD) and cell viability (CV) are key performance indicators of cell culture
processes in biopharmaceutical production of biologics and vaccines. Traditional methods …

To face the coronavirus disease 2019 pandemic caused by the severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) virus, our institute has developed the rVSV‐ΔG …

In this work, laboratory-and large-scale methods were tested for purification of a human
immunodeficiency virus (HIV) vaccine candidate, based on recombinant vesicular stomatitis …

Vesicular stomatitis virus (VSV) remains an attractive platform for a potential HIV-1 vaccine
but hurdles remain, such as selection of a highly immunogenic HIV-1 Envelope (Env) with a …

Currently, no effective vaccine to prevent human immunodeficiency virus (HIV) infection is
available, and various platforms are being examined. The vesicular stomatitis virus (VSV) …