Nucleophosmin (NPM1) is a mostly nucleolar protein with crucial functions in cell growth
and homeostasis, including regulation of ribosome biogenesis and stress response. Such …

In metal-peptide interactions, cations form stable complexes through bonds with
coordinating groups as side chains of amino acids. These compounds, among other things …

The pharmacodynamic and pharmacokinetic properties of bioactive peptides can be
modulated by introducing conformational constraints such as intramolecular …

Herein we present a comparative study of the effects of isoquinoline alkaloids belonging to
benzo [c] phenanthridine and berberine families on β-amyloid aggregation. Results …

Herein the effects of three platinum complexes, namely (SP-4-2)-(2, 2′-bipyridine)
dichloridoplatinum (II), Pt-bpy,(SP-4-2)-dichlorido (1, 10-phenanthroline) platinum (II), Pt …

Acute myeloid leukemia (AML) is a clinically and a molecularly heterogeneous disease
characterized by the accumulation of undifferentiated and uncontrolled proliferation of …

The apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1), the main AP-endonuclease of
the DNA base excision repair pathway, is a key molecule of interest to researchers due to its …

Supramolecular assemblies of short peptides are experiencing a stimulating flowering.
Herein, we report a novel class of bioinspired pentapeptides, not bearing Phe, that form …

Platinum (II) complexes with different cinnamic acid derivatives as ligands were investigated
for their ability to inhibit the aggregation process of amyloid systems derived from Aβ, Yeast …

The deposition of aggregated human islet amyloid polypeptide (hIAPP) in the pancreas, that
has been associated with β-cell dysfunction, is one of the common pathological features of …