Auditory dysfunction in schizophrenia: integrating clinical and basic features
Schizophrenia is a complex neuropsychiatric disorder that is associated with persistent
psychosocial disability in affected individuals. Although studies of schizophrenia have …
psychosocial disability in affected individuals. Although studies of schizophrenia have …
The glutamate hypothesis of schizophrenia: evidence from human brain tissue studies
W Hu, ML MacDonald, DE Elswick… - Annals of the New York …, 2015 - Wiley Online Library
A number of studies have indicated that antagonists of the N‐methyl‐d‐aspartate subtypes
of glutamate receptors can cause schizophrenia‐like symptoms in healthy individuals and …
of glutamate receptors can cause schizophrenia‐like symptoms in healthy individuals and …
Laminar structure of spontaneous and sensory-evoked population activity in auditory cortex
Spontaneous activity plays an important role in the function of neural circuits. Although many
similarities between spontaneous and sensory-evoked neocortical activity have been …
similarities between spontaneous and sensory-evoked neocortical activity have been …
Complementary control of sensory adaptation by two types of cortical interneurons
RG Natan, JJ Briguglio, L Mwilambwe-Tshilobo… - elife, 2015 - elifesciences.org
Reliably detecting unexpected sounds is important for environmental awareness and
survival. By selectively reducing responses to frequently, but not rarely, occurring sounds …
survival. By selectively reducing responses to frequently, but not rarely, occurring sounds …
A corticothalamic circuit for dynamic switching between feature detection and discrimination
Sensory processing must be sensitive enough to encode faint signals near the noise floor
but selective enough to differentiate between similar stimuli. Here we describe a layer 6 …
but selective enough to differentiate between similar stimuli. Here we describe a layer 6 …
[HTML][HTML] Integration of visual information in auditory cortex promotes auditory scene analysis through multisensory binding
How and where in the brain audio-visual signals are bound to create multimodal objects
remains unknown. One hypothesis is that temporal coherence between dynamic …
remains unknown. One hypothesis is that temporal coherence between dynamic …
Robustness of cortical topography across fields, laminae, anesthetic states, and neurophysiological signal types
W Guo, AR Chambers, KN Darrow… - Journal of …, 2012 - Soc Neuroscience
Topographically organized maps of the sensory receptor epithelia are regarded as
cornerstones of cortical organization as well as valuable readouts of diverse biological …
cornerstones of cortical organization as well as valuable readouts of diverse biological …
A critical period for auditory thalamocortical connectivity
Neural circuits are shaped by experience during periods of heightened brain plasticity in
early postnatal life. Exposure to acoustic features produces age-dependent changes …
early postnatal life. Exposure to acoustic features produces age-dependent changes …
Linking topography to tonotopy in the mouse auditory thalamocortical circuit
TA Hackett, TR Barkat, BMJ O'Brien… - Journal of …, 2011 - Soc Neuroscience
The mouse sensory neocortex is reported to lack several hallmark features of topographic
organization such as ocular dominance and orientation columns in primary visual cortex or …
organization such as ocular dominance and orientation columns in primary visual cortex or …
Schizophrenia from a neural circuitry perspective: advancing toward rational pharmacological therapies
Schizophrenia is a severe disorder that disrupts the function of multiple brain systems,
resulting in impaired social and occupational functioning. The etiology and pathogenesis of …
resulting in impaired social and occupational functioning. The etiology and pathogenesis of …