Azole-resistant Aspergillus fumigatus in the environment: Identifying key reservoirs and hotspots of antifungal resistance
C Burks, A Darby, L Gómez Londoño… - PLoS …, 2021 - journals.plos.org
Aspergillus fumigatus is an opportunistic human pathogen that causes aspergillosis, a
spectrum of environmentally acquired respiratory illnesses. It has a cosmopolitan distribution …
spectrum of environmentally acquired respiratory illnesses. It has a cosmopolitan distribution …
Invasive candidiasis
Invasive candidiasis is an important fungal disease caused by Candida albicans and,
increasingly, non-albicans Candida pathogens. Invasive Candida infections originate most …
increasingly, non-albicans Candida pathogens. Invasive Candida infections originate most …
[HTML][HTML] European candidaemia is characterised by notable differential epidemiology and susceptibility pattern: Results from the ECMM Candida III study
MC Arendrup, S Arikan-Akdagli, KM Jørgensen… - Journal of Infection, 2023 - Elsevier
The objectives of this study were to assess Candida spp. distribution and antifungal
resistance of candidaemia across Europe. Isolates were collected as part of the third ECMM …
resistance of candidaemia across Europe. Isolates were collected as part of the third ECMM …
Candidemia: evolution of drug resistance and novel therapeutic approaches
AM Tortorano, A Prigitano, G Morroni… - Infection and Drug …, 2021 - Taylor & Francis
Candidemia and invasive candidiasis are the most common healthcare-associated invasive
fungal infections, with a crude mortality rate of 25–50%. Candida albicans remains the most …
fungal infections, with a crude mortality rate of 25–50%. Candida albicans remains the most …
Molecular mechanisms of acquired antifungal drug resistance in principal fungal pathogens and EUCAST guidance for their laboratory detection and clinical …
TR Rogers, PE Verweij, M Castanheira… - Journal of …, 2022 - academic.oup.com
The increasing incidence and changing epidemiology of invasive fungal infections continue
to present many challenges to their effective management. The repertoire of antifungal drugs …
to present many challenges to their effective management. The repertoire of antifungal drugs …
Overview on the Infections Related to Rare Candida Species
Atypical Candida spp. infections are rising, mostly due to the increasing numbers of
immunocompromised patients. The most common Candida spp. is still Candida albicans; …
immunocompromised patients. The most common Candida spp. is still Candida albicans; …
Candida parapsilosis complex in the clinical setting
M Govrins, C Lass-Flörl - Nature Reviews Microbiology, 2024 - nature.com
Representatives of the Candida parapsilosis complex are important yeast species causing
human infections, including candidaemia as one of the leading diseases. This complex …
human infections, including candidaemia as one of the leading diseases. This complex …
Aspergillus fumigatus and aspergillosis: From basics to clinics
The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by
causing numerous invasive infections and a notable mortality in humans, especially in …
causing numerous invasive infections and a notable mortality in humans, especially in …
Incidence of candidemia is higher in COVID-19 versus non-COVID-19 patients, but not driven by intrahospital transmission
M Machado, A Estévez, C Sánchez-Carrillo, J Guinea… - Journal of Fungi, 2022 - mdpi.com
There is scarce information on the actual incidence of candidemia in COVID-19 patients. In
addition, comparative studies of candidemia episodes in COVID-19 and non-COVID-19 …
addition, comparative studies of candidemia episodes in COVID-19 and non-COVID-19 …
[HTML][HTML] Clinical practice guideline for the therapeutic drug monitoring of voriconazole in non-Asian and Asian adult patients: consensus review by the Japanese …
Y Takesue, Y Hanai, K Oda, Y Hamada, T Ueda… - Clinical Therapeutics, 2022 - Elsevier
Purpose Voriconazole, an antifungal drug, is metabolized by a cytochrome P450 isozyme.
Increased adverse effects are observed in Asians because of the high rate of poor …
Increased adverse effects are observed in Asians because of the high rate of poor …