Azole-resistant Aspergillus fumigatus in the environment: Identifying key reservoirs and hotspots of antifungal resistance

C Burks, A Darby, L Gómez Londoño… - PLoS …, 2021 - journals.plos.org
Aspergillus fumigatus is an opportunistic human pathogen that causes aspergillosis, a
spectrum of environmentally acquired respiratory illnesses. It has a cosmopolitan distribution …

Invasive candidiasis

C Lass-Flörl, SS Kanj, NP Govender… - Nature Reviews …, 2024 - nature.com
Invasive candidiasis is an important fungal disease caused by Candida albicans and,
increasingly, non-albicans Candida pathogens. Invasive Candida infections originate most …

[HTML][HTML] European candidaemia is characterised by notable differential epidemiology and susceptibility pattern: Results from the ECMM Candida III study

MC Arendrup, S Arikan-Akdagli, KM Jørgensen… - Journal of Infection, 2023 - Elsevier
The objectives of this study were to assess Candida spp. distribution and antifungal
resistance of candidaemia across Europe. Isolates were collected as part of the third ECMM …

Candidemia: evolution of drug resistance and novel therapeutic approaches

AM Tortorano, A Prigitano, G Morroni… - Infection and Drug …, 2021 - Taylor & Francis
Candidemia and invasive candidiasis are the most common healthcare-associated invasive
fungal infections, with a crude mortality rate of 25–50%. Candida albicans remains the most …

Molecular mechanisms of acquired antifungal drug resistance in principal fungal pathogens and EUCAST guidance for their laboratory detection and clinical …

TR Rogers, PE Verweij, M Castanheira… - Journal of …, 2022 - academic.oup.com
The increasing incidence and changing epidemiology of invasive fungal infections continue
to present many challenges to their effective management. The repertoire of antifungal drugs …

Overview on the Infections Related to Rare Candida Species

S Kumar, A Kumar, M Roudbary, R Mohammadi… - Pathogens, 2022 - mdpi.com
Atypical Candida spp. infections are rising, mostly due to the increasing numbers of
immunocompromised patients. The most common Candida spp. is still Candida albicans; …

Candida parapsilosis complex in the clinical setting

M Govrins, C Lass-Flörl - Nature Reviews Microbiology, 2024 - nature.com
Representatives of the Candida parapsilosis complex are important yeast species causing
human infections, including candidaemia as one of the leading diseases. This complex …

Aspergillus fumigatus and aspergillosis: From basics to clinics

A Arastehfar, A Carvalho, J Houbraken… - Studies in …, 2021 - ingentaconnect.com
The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by
causing numerous invasive infections and a notable mortality in humans, especially in …

Incidence of candidemia is higher in COVID-19 versus non-COVID-19 patients, but not driven by intrahospital transmission

M Machado, A Estévez, C Sánchez-Carrillo, J Guinea… - Journal of Fungi, 2022 - mdpi.com
There is scarce information on the actual incidence of candidemia in COVID-19 patients. In
addition, comparative studies of candidemia episodes in COVID-19 and non-COVID-19 …

[HTML][HTML] Clinical practice guideline for the therapeutic drug monitoring of voriconazole in non-Asian and Asian adult patients: consensus review by the Japanese …

Y Takesue, Y Hanai, K Oda, Y Hamada, T Ueda… - Clinical Therapeutics, 2022 - Elsevier
Purpose Voriconazole, an antifungal drug, is metabolized by a cytochrome P450 isozyme.
Increased adverse effects are observed in Asians because of the high rate of poor …