Exhaled breath is a promising specimen for in vivo drug analysis. The analysis of non-
volatile drugs (NVDs) in exhaled breath is especially valuable due to the clinical prevalence …

This goal of this minireview is to introduce the reader to the area of research concerned with
exhaled breath analysis for the purpose of detecting abnormal levels of physiologically …

While brown adipose tissue (BAT) is activated by the beta-3-adrenergic receptor (ADRB3) in
rodents, in human brown adipocytes, the ADRB2 is dominantly present and responsible for …

Introduction: Inhaled drugs are important in the treatment of many lung pathologies, but to be
therapeutically effective they must reach unbound concentrations at their effect site in the …

A microwave-induced air–assisted liquid–liquid microextraction method has been proposed
for the pretreatment/quantization of salbutamol in exhaled breath condensate (EBC) …

The exhaled breath condensate (EBC) presents a simple and non-invasive alternative
approach for bioequivalence assessments and therapeutic drug monitoring of inhaled …

Background Treating pulmonary infections by administering drugs via oral inhalation
represents an attractive alternative to usual routes of administration. However, the local …

Background Abdominal pain is a frequent symptom of IgE-mediated food allergy with limited
therapeutic options. Visceral smooth muscle cell relaxation can be induced through beta …

Background: Historically, pharmacokinetic (PK) studies and therapeutic drug monitoring
(TDM) have relied on plasma as a sampling matrix. Noninvasive sampling matrices, such as …

Exhaled breath condensate (EBC) has recently emerged as a noninvasive alternative to
obtain a respiratory sample to study airway drug concentration. The aim of this work is to …