High-Mobility Group (HMG) chromosomal proteins are the most numerous nuclear non-
histone proteins. HMGB domain proteins are the most abundant and well-studied HMG …

High Mobility Group Box (HMGB) proteins are small architectural DNA binding proteins that
regulate multiple genomic processes such as DNA damage repair, nucleosome sliding …

Processes like cellular senescence are characterized by complex events giving rise to
heterogeneous cell populations. However, the early molecular events driving this cascade …

Histone modifications influence higher-order chromatin structures at individual epigenomic
states and chromatin environments to regulate gene expression. However, genome-wide …

Background: Cardiovascular disease is associated with epigenomic changes in the heart;
however, the endogenous structure of cardiac myocyte chromatin has never been …

Cardiovascular disease (CVD) is the most fatal disease that causes sudden death, and
inflammation contributes substantially to its occurrence and progression. The prevalence of …

Embryonic and postnatal life depend on the uninterrupted function of cardiac muscle cells.
These cells, termed cardiomyocytes, display many fascinating behaviors, including complex …

If unifying principles could be revealed for how the same genome encodes different
eukaryotic cells and for how genetic variability and environmental input are integrated to …

Mass spectrometry-based proteomics is a sophisticated identification tool specializing in
portraying protein dynamics at a molecular level. Proteomics provides biologists with a …

Cardiomyopathies (CMPs) are a heterogeneous group of myocardial diseases accountable
for the majority of cases of heart failure (HF) and/or sudden cardiac death (SCD) worldwide …