Metabolic engineering aims to improve the production of economically valuable molecules
through the genetic manipulation of microbial metabolism. While the discipline is a little over …

According to Darwin's theory, endless evolution leads to a revolution. One such example is
the Clustered Regularly Interspaced Palindromic Repeats (CRISPR)–Cas system, an …

Substrate inhibition of enzymes can be a major obstacle to the production of valuable
chemicals in engineered microorganisms. Here, we show substrate inhibition of lycopene …

Microbial bioproduction of chemicals, proteins, and primary metabolites from cheap carbon
sources is currently an advancing area in industrial research. The model yeast …

Metabolic engineering aims to develop efficient cell factories by rewiring cellular
metabolism. As one of the most commonly used cell factories, Saccharomyces cerevisiae …

Among non-conventional yeasts of industrial interest, the dimorphic oleaginous yeast
Yarrowia lipolytica appears as one of the most attractive for a large range of white …

Recombinant protein production emerged in the early 1980s with the development of
genetic engineering tools, which represented a compelling alternative to protein extraction …

Quickly and precisely gain genetically enhanced breeding elites with value-adding
performance traits is desired by the crop breeders all the time. The present of gene editing …

CRISPR/Cas9 based systems have emerged as versatile platforms for precision genome
editing in a wide range of organisms. Here we have developed powerful CRISPR/Cas9 tools …

The nonconventional, oleaginous yeast, Yarrowia lipolytica is rapidly emerging as a
valuable host for the production of a variety of both lipid and nonlipid chemical products …