Carbon monoxide (CO) poisoning affects 50,000 people a year in the United States. The
clinical presentation runs a spectrum, ranging from headache and dizziness to coma and …

The heme oxygenase-1 (HO-1) enzyme system remains an attractive therapeutic target for
the treatment of inflammatory conditions. HO-1, a cellular stress protein, serves a vital …

Air pollution is a global health concern. Particulate matter (PM) 2.5, a component of ambient
air pollution, has been identified by the World Health Organization as one of the pollutants …

Exposure to ambient air pollution is associated with adverse cardiovascular outcomes.
These are manifested through several, likely overlapping, pathways including at the …

Background: Dilated cardiomyopathy is a frequent disease responsible for 40–50% of cases
of heart failure. Idiopathic cardiomyopathy is a primary disorder often related to …

Background Smoking is a well-established risk factor for ST-segment elevation myocardial
infarction (STEMI); however, once STEMI occurs, smoking has been associated with …

Diabetic cardiomyopathy is one of the diabetes mellitus-induced cardiovascular
complications that can result in heart failure in severe cases, which is characterized by …

The world population is aging rapidly, and by some estimates, the number of people older
than 60 will double in the next 30 years. With the increase in life expectancy, adverse effects …

Carbon monoxide (CO), generated by heme oxygenase (HO), has been considered a
signaling molecule in both the cardiovascular and central nervous systems. The biological …

Heme oxygenase (HO) enzymes are responsible for the main oxidative step in heme
degradation, generating equimolar amounts of free iron, biliverdin and carbon monoxide …