Over the past decade, there has been an unprecedented international focus on improved
quality and availability of medical care, which has reignited interest in clinical automation …

In this paper we present the preliminary clinical results obtained with a PID control scheme
for propofol and remifentanil coadministration during general anesthesia. The bispectral …

This paper describes the design and evaluation of a controller for multi-input single-output
(MISO) propofol-remifentanil anesthesia, guided by feedback from a measure of depth-of …

In this paper, a new method to estimate the states and the parameters of the anesthesia
process is proposed and compared to a Moving Horizon Estimator (MHE) approach. The …

This letter presents an extended moving horizon observer to estimate both the states and the
pharmacodynamic (PD) parameters of an anesthesia model, based on real data. The inputs …

The thesis discusses closed-loop control of the hypnotic and the analgesic components of
anesthesia. The objective of the work has been to develop a system which independently …

Closed-loop control of anesthesia is expected to decrease drug dosage and wake up time
while increasing patient safety and decreasing the work load of the anesthesiologist. The …

Automated Drug Delivery in Anesthesia provides a full review of available tools and
methods on the drug delivery of anesthesia, bridging the gap between academic …

The design of a fractional order model reference adaptive control for anesthesia based on a
fractional order model is proposed in the paper. This model gets around many difficulties in …

The depth of anesthesia (DoA) is a crucial feature in general anesthesia. Nowadays the DoA
is usually evaluated by the bispectral index (BIS). According to the surgical procedure …