Cancer vaccines: the next immunotherapy frontier
MJ Lin, J Svensson-Arvelund, GS Lubitz, A Marabelle… - Nature cancer, 2022 - nature.com
After several decades, therapeutic cancer vaccines now show signs of efficacy and potential
to help patients resistant to other standard-of-care immunotherapies, but they have yet to …
to help patients resistant to other standard-of-care immunotherapies, but they have yet to …
Diffuse large B-cell lymphoma
LH Sehn, G Salles - New England Journal of Medicine, 2021 - Mass Medical Soc
Diffuse Large B-Cell Lymphoma DLBCL, an aggressive cancer, accounts for about 30% of
all lymphomas. Empirical combination chemotherapy cures about 65% of patients initially …
all lymphomas. Empirical combination chemotherapy cures about 65% of patients initially …
[HTML][HTML] Polatuzumab vedotin in previously untreated diffuse large B-cell lymphoma
H Tilly, F Morschhauser, LH Sehn… - … England Journal of …, 2022 - Mass Medical Soc
Background Diffuse large B-cell lymphoma (DLBCL) is typically treated with rituximab,
cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP). However, only 60 …
cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP). However, only 60 …
Atorvastatin for anthracycline-associated cardiac dysfunction: the STOP-CA randomized clinical trial
Importance Anthracyclines treat a broad range of cancers. Basic and retrospective clinical
data have suggested that use of atorvastatin may be associated with a reduction in cardiac …
data have suggested that use of atorvastatin may be associated with a reduction in cardiac …
[HTML][HTML] Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: a report from the COVID-19 and Cancer …
Background Patients with cancer may be at high risk of adverse outcomes from severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We analyzed a cohort of …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We analyzed a cohort of …
Polatuzumab vedotin in relapsed or refractory diffuse large B-cell lymphoma
LH Sehn, AF Herrera, CR Flowers… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Patients with transplantation-ineligible relapsed/refractory (R/R) diffuse large B-
cell lymphoma (DLBCL) fare poorly, with limited treatment options. The antibody-drug …
cell lymphoma (DLBCL) fare poorly, with limited treatment options. The antibody-drug …
[HTML][HTML] Tisagenlecleucel in adult relapsed or refractory diffuse large B-cell lymphoma
SJ Schuster, MR Bishop, CS Tam… - … England Journal of …, 2019 - Mass Medical Soc
Background Patients with diffuse large B-cell lymphoma that is refractory to primary and
second-line therapies or that has relapsed after stem-cell transplantation have a poor …
second-line therapies or that has relapsed after stem-cell transplantation have a poor …
ROBUST: a phase III study of lenalidomide plus R-CHOP versus placebo plus R-CHOP in previously untreated patients with ABC-type diffuse large B-cell lymphoma
GS Nowakowski, A Chiappella… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Patients with the activated B-cell-like (ABC) subtype of diffuse large B-cell
lymphoma (DLBCL) historically showed inferior survival with standard rituximab plus …
lymphoma (DLBCL) historically showed inferior survival with standard rituximab plus …
Evolution of cancer pharmacological treatments at the turn of the third millennium
The medical history of cancer began millennia ago. Historical findings of patients with
cancer date back to ancient Egyptian and Greek civilizations, where this disease was …
cancer date back to ancient Egyptian and Greek civilizations, where this disease was …
Targeted sequencing in DLBCL, molecular subtypes, and outcomes: a Haematological Malignancy Research Network report
Based on the profile of genetic alterations occurring in tumor samples from selected diffuse
large B-cell lymphoma (DLBCL) patients, 2 recent whole-exome sequencing studies …
large B-cell lymphoma (DLBCL) patients, 2 recent whole-exome sequencing studies …