Many features of the environment have been found to exert an important influence on
cardiovascular disease (CVD) risk, progression, and severity. Changes in the environment …

Patients recovering from COVID-19 often report symptoms of exhaustion, fatigue and
dyspnoea and present with exercise intolerance persisting for months post-infection …

Background Some patients with COVID-19 who have recovered from the acute infection
after experiencing only mild symptoms continue to exhibit persistent exertional limitation that …

INTRODUCTION To date, 559 humans have been flown into space, but long-duration (> 300
days) missions are rare (n= 8 total). Long-duration missions that will take humans to Mars …

Left ventricular hypertrophy is a leading risk factor for cardiovascular morbidity and mortality.
Although reverse ventricular remodelling was long thought to be irreversible, evidence from …

Despite declines in heart failure morbidity and mortality with current therapies,
rehospitalization rates remain distressingly high, substantially affecting individuals, society …

Postural orthostatic tachycardia syndrome (POTS), the most common form of orthostatic
intolerance in young people, affects approximately 500,000 people in the United States …

National space agencies and private corporations aim at an extended presence of humans
in space in the medium to long term. Together with currently suboptimal technology …

The field of human space travel is in the midst of a dramatic revolution. Upcoming missions
are looking to push the boundaries of space travel, with plans to travel for longer distances …

Background—It is unclear whether, and to what extent, the striking cardiac morphological
manifestations of endurance athletes are a result of exercise training or a genetically …