The role of reactive oxygen species in arsenic toxicity
Y Hu, J Li, B Lou, R Wu, G Wang, C Lu, H Wang, J Pi… - Biomolecules, 2020 - mdpi.com
Arsenic poisoning is a global health problem. Chronic exposure to arsenic has been
associated with the development of a wide range of diseases and health problems in …
associated with the development of a wide range of diseases and health problems in …
[HTML][HTML] Mitochondrial calcium transport and the redox nature of the calcium-induced membrane permeability transition
Mitochondria possess a Ca 2+ transport system composed of separate Ca 2+ influx and
efflux pathways. Intramitochondrial Ca 2+ concentrations regulate oxidative …
efflux pathways. Intramitochondrial Ca 2+ concentrations regulate oxidative …
The mitochondrial permeability transition: nexus of aging, disease and longevity
H Rottenberg, JB Hoek - Cells, 2021 - mdpi.com
The activity of the mitochondrial permeability transition pore, mPTP, a highly regulated multi-
component mega-channel, is enhanced in aging and in aging-driven degenerative …
component mega-channel, is enhanced in aging and in aging-driven degenerative …
Arsenite induces testicular oxidative stress in vivo and in vitro leading to ferroptosis
P Meng, S Zhang, X Jiang, S Cheng, J Zhang… - Ecotoxicology and …, 2020 - Elsevier
Ferroptosis is a newly identified form of cell death characterized by accumulation of
intracellular iron and requirement of lipid peroxidation. However, whether arsenite triggers …
intracellular iron and requirement of lipid peroxidation. However, whether arsenite triggers …
Intracellular behavior of Nocardia seriolae and its apoptotic effect on RAW264.7 macrophages
W Liu, Y Deng, A Tan, F Zhao, O Chang… - Frontiers in Cellular …, 2023 - frontiersin.org
Nocardia seriolae, an intracellular gram-positive pathogen, is prone to infecting
immunocompromised and surface-damaged fish, causing serious losses to the aquaculture …
immunocompromised and surface-damaged fish, causing serious losses to the aquaculture …
Arsenite impinges on endoplasmic reticulum-mitochondria crosstalk to elicit mitochondrial ROS formation and downstream toxicity
Arsenite is an important carcinogen and toxic compound, causing various deleterious effects
through multiple mechanisms. In this review, we focused on mitochondrial ROS (mitoROS) …
through multiple mechanisms. In this review, we focused on mitochondrial ROS (mitoROS) …
Mitochondrial oxidative stress is the general reason for apoptosis induced by different-valence heavy metals in cells and mitochondria
SM Korotkov - International Journal of Molecular Sciences, 2023 - mdpi.com
This review analyzes the causes and consequences of apoptosis resulting from oxidative
stress that occurs in mitochondria and cells exposed to the toxic effects of different-valence …
stress that occurs in mitochondria and cells exposed to the toxic effects of different-valence …
[HTML][HTML] Calcium signals between the ryanodine receptor-and mitochondria critically regulate the effects of arsenite on mitochondrial superoxide formation and on the …
A low concentration of arsenite (6 h), selectively stimulating the intraluminal crosstalk
between the inositol-1, 4, 5-triphosphate receptor and the ryanodine receptor (RyR) …
between the inositol-1, 4, 5-triphosphate receptor and the ryanodine receptor (RyR) …
[HTML][HTML] Enhanced sciatic nerve regeneration by relieving iron-overloading and organelle stress with the nanofibrous P (MMD-co-LA)/DFO conduits
L Han, X Dong, T Qiu, Z Dou, L Wu, H Dai - Materials Today Bio, 2022 - Elsevier
Wallerian degeneration after peripheral nerve injury (PNI), that is, the autonomous
degeneration of distal axons, leads to an imbalance of iron homeostasis and easily induces …
degeneration of distal axons, leads to an imbalance of iron homeostasis and easily induces …
Deferoxamine Promotes Peripheral Nerve Regeneration by Enhancing Schwann Cell Function and Promoting Axon Regeneration of Dorsal Root Ganglion
T Zhang, J Zhao, Y Guan, X Li, J Bai, X Song, Z Jia… - Neuroscience, 2023 - Elsevier
Deferoxamine (DFO) is a potent iron chelator for clinical treatment of various diseases.
Recent studies have also shown its potential to promote vascular regeneration during …
Recent studies have also shown its potential to promote vascular regeneration during …