Retinoid acid (RA) is synthesized mainly in the liver and has multiple functions in
development, cell differentiation and proliferation, and regulation of inflammation. RA has …

One of the side effects of oral antiaging retinoids is increased hair shedding. Retinoids
promote the expression of TGF‐β2 from fibroblasts, which stimulate collagen expression but …

Different topical agents have been used to accelerate wound healing. The purpose of this
study is to compare the safety and efficacy of topical application of the extract of Hypericum …

The transcriptional regulators underlying induction and differentiation of dense connective
tissues such as tendon and related fibrocartilaginous tissues (meniscus and annulus …

Morphogenetic events are driven by cell-generated physical forces and complex cellular
dynamics. To improve our capacity to predict developmental effects from chemical-induced …

Mucous membrane pemphigoid (MMP) is a systemic mucosal scarring disease, commonly
causing blindness, for which there is no antifibrotic therapy. Aldehyde dehydrogenase family …

Transforming growth factor beta (TGF-β) is the main cytokine responsible for the induction of
the epithelial-mesenchymal transition of breast cancer cells, which is a hallmark of tumor …

Epithelial–mesenchymal transition (EMT) in retinal pigment epithelial (RPE) cells plays a
key role in proliferative retinal diseases such as age-related macular degeneration by …

Retinoid X receptor (RXR), particularly RXRα, has been implicated in cardiovascular
diseases. However, the functional role of RXR activation in myocardial infarction (MI) …

Metalloproteinases (MMP) s regulate developmental processes, control angiogenesis and
wound healing, participate in the formation of immune receptors, and are expressed in stem …