Disturbance of endoplasmic reticulum (ER) homeostasis triggered by the accumulation of
unfolded proteins and advanced glycation end-products (AGEs) plays a major role in …

Diabetic cardiovascular diseases (DCVDs) are the most common complications of diabetes
mellitus and are considered to be one of the most important threats to global health and an …

Background Food allergy (FA) is one of the most common chronic conditions in children with
an increasing prevalence facilitated by the exposure to environmental factors in predisposed …

Osteocytes are extremely sensitive to mechanical loading and govern bone remodeling
process. Advanced glycation end products (AGEs) have the capacity to induce osteocyte …

The glycation of various biomolecules is the root cause of many pathological conditions
associated with diabetic nephropathy and end-stage kidney disease. Glycation imbalances …

Diabetes mellitus is an arising public health concern, and diabetic foot is one of the most
common complications of diabetes. Current management for diabetic foot cannot reach …

目的: 探讨在高糖条件下小鼠肾小球系膜细胞(MGMC) 中lncRNA-Gm4419 与miR-7214-3p
结合对炎症, 纤维化和增殖的影响. 方法: qRT-PCR 测定低糖组(5.5 mmol/L 葡萄糖+ 19.5 …

This study aimed to elucidate the impact of advanced glycation end products (AGEs) and
glucose shock on cardiomyocyte viability, gene expression, cardiac biomarkers, and cardiac …

1% of Canada's population is projected to be affected by type 2 diabetes by 2025. Diabetic
patients suffer from micro-and macrovascular diseases that arise from aberrant …

Objective: To investigate the effects of lncRNA-Gm4419 binding with miR-7214-3p on
inflammation, fibrosis, and proliferation in mouse glomerular mesangial cells (MGMCs) …