Composition, structure and mechanical properties define performance of pulmonary surfactant membranes and films
E Parra, J Pérez-Gil - Chemistry and physics of lipids, 2015 - Elsevier
The respiratory surface in the mammalian lung is stabilized by pulmonary surfactant, a
membrane-based system composed of multiple lipids and specific proteins, the primary …
membrane-based system composed of multiple lipids and specific proteins, the primary …
[HTML][HTML] Structure-function relationships in pulmonary surfactant membranes: from biophysics to therapy
E Lopez-Rodriguez, J Pérez-Gil - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
Pulmonary surfactant is an essential lipid–protein complex to maintain an operative
respiratory surface at the mammalian lungs. It reduces surface tension at the alveolar air …
respiratory surface at the mammalian lungs. It reduces surface tension at the alveolar air …
[HTML][HTML] Structure of pulmonary surfactant membranes and films: the role of proteins and lipid–protein interactions
J Pérez-Gil - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2008 - Elsevier
The pulmonary surfactant system constitutes an excellent example of how dynamic
membrane polymorphism governs some biological functions through specific lipid–lipid …
membrane polymorphism governs some biological functions through specific lipid–lipid …
Cholesterol rules: direct observation of the coexistence of two fluid phases in native pulmonary surfactant membranes at physiological temperatures
Pulmonary surfactant, the lipid-protein material that stabilizes the respiratory surface of the
lungs, contains approximately equimolar amounts of saturated and unsaturated …
lungs, contains approximately equimolar amounts of saturated and unsaturated …
Pulmonary surfactant metabolism in the alveolar airspace: Biogenesis, extracellular conversions, recycling
B Olmeda, M Martínez-Calle, J Pérez-Gil - Annals of Anatomy …, 2017 - Elsevier
Pulmonary surfactant is a lipid–protein complex that lines and stabilizes the respiratory
interface in the alveoli, allowing for gas exchange during the breathing cycle. At the same …
interface in the alveoli, allowing for gas exchange during the breathing cycle. At the same …
Interfacial properties of pulmonary surfactant layers
R Wüstneck, J Perez-Gil, N Wüstneck, A Cruz… - Advances in colloid and …, 2005 - Elsevier
The composition of the pulmonary surfactant and the border conditions of normal human
breathing are relevant to characterize the interfacial behavior of pulmonary layers. Based on …
breathing are relevant to characterize the interfacial behavior of pulmonary layers. Based on …
Comparative transcriptome analyses indicate molecular homology of zebrafish swimbladder and mammalian lung
The fish swimbladder is a unique organ in vertebrate evolution and it functions for regulating
buoyancy in most teleost species. It has long been postulated as a homolog of the tetrapod …
buoyancy in most teleost species. It has long been postulated as a homolog of the tetrapod …
Special relationship between sterols and oxygen: were sterols an adaptation to aerobic life?
AM Galea, AJ Brown - Free Radical Biology and Medicine, 2009 - Elsevier
A fascinating link between sterols and molecular oxygen (O2) has been a common thread
running through the fundamental work of Konrad Bloch, who elucidated the biosynthetic …
running through the fundamental work of Konrad Bloch, who elucidated the biosynthetic …
A central theory of biology
JS Torday - Medical hypotheses, 2015 - Elsevier
The history of physiologic cellular–molecular interrelationships can be traced all the way
back to the unicellular state by following the pathway formed by lipids ubiquitously …
back to the unicellular state by following the pathway formed by lipids ubiquitously …
The lipid composition of autophagic vacuoles regulates expression of multilamellar bodies
Multilamellar bodies (MLBs) are responsible for surfactant secretion in type II alveolar cells
but also accumulate in other cell types under pathological conditions, including cancer and …
but also accumulate in other cell types under pathological conditions, including cancer and …