Compared with all other racial and ethnic groups in the United States, African Americans are
disproportionally affected by lung cancer, both in terms of incidence and survival. It is likely …

Nucleic acids form not only the canonical double helix (duplex) but also the non-canonical
(non-double helix) structures such as triplexes, G-quadruplexes, and i-motifs. The formation …

Importance Using race and ethnicity in clinical prediction models can reduce or inadvertently
increase racial and ethnic disparities in medical decisions. Objective To compare eligibility …

Avoidable differences in the care and outcomes of patients with cancer (ie, cancer care
disparities) emerge or worsen with discoveries of new, more effective approaches to cancer …

Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer
with an abysmal prognosis rate over the last few decades. Early diagnosis and prevention …

Background Checkpoint-inhibitor immunotherapies have had a profound effect in the
treatment of cancer by inhibiting down-regulation of T-cell response to malignancy. The …

Non‐small‐cell lung cancer (NSCLC) is one of the main causes of death induced by cancer
globally. However, the molecular aberrations in NSCLC patients remain unclearly. In the …

Background MicroRNAs (miRNA) recently evolved as potential cancer biomarkers.
Therefore, the aim of the present study was to evaluate the prognostic impact of eight …

Kirsten rat sarcoma viral oncogene homolog (KRAS) aberrations frequently occur in patients
with lung cancer. Oncogenic KRAS is characterized by excessive reactive oxygen species …

Background Lung cancer has been a common malignant tumor with a leading cause of
morbidity and mortality, current molecular targets are woefully lacking comparing to the …