[HTML][HTML] Acyl-CoA: diacylglycerol acyltransferase: Properties, physiological roles, metabolic engineering and intentional control

G Chen, JL Harwood, MJ Lemieux, SJ Stone… - Progress in Lipid …, 2022 - Elsevier
Acyl-CoA: diacylglycerol acyltransferase (DGAT, EC 2.3. 1.20) catalyzes the last reaction in
the acyl-CoA-dependent biosynthesis of triacylglycerol (TAG). DGAT activity resides mainly …

Whole-genome regression and prediction methods applied to plant and animal breeding

G de Los Campos, JM Hickey, R Pong-Wong… - Genetics, 2013 - academic.oup.com
Genomic-enabled prediction is becoming increasingly important in animal and plant
breeding and is also receiving attention in human genetics. Deriving accurate predictions of …

Whole-genome sequencing of 234 bulls facilitates mapping of monogenic and complex traits in cattle

HD Daetwyler, A Capitan, H Pausch, P Stothard… - Nature …, 2014 - nature.com
The 1000 bull genomes project supports the goal of accelerating the rates of genetic gain in
domestic cattle while at the same time considering animal health and welfare by providing …

Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis

CLE Yen, SJ Stone, S Koliwad, C Harris… - Journal of lipid …, 2008 - ASBMB
Triacylglycerols (triglycerides)(TGs) are the major storage molecules of metabolic energy
and FAs in most living organisms. Excessive accumulation of TGs, however, is associated …

Enzymes of triacylglycerol synthesis and their regulation

RA Coleman, DP Lee - Progress in lipid research, 2004 - Elsevier
Since the pathways of glycerolipid biosynthesis were elucidated in the 1950's, considerable
knowledge has been gained about the enzymes that catalyze the lipid biosynthetic reactions …

The impact of genetic relationship information on genomic breeding values in German Holstein cattle

D Habier, J Tetens, FR Seefried, P Lichtner… - Genetics Selection …, 2010 - Springer
Background The impact of additive-genetic relationships captured by single nucleotide
polymorphisms (SNPs) on the accuracy of genomic breeding values (GEBVs) has been …

Acyl-CoA: diacylglycerol acyltransferase: molecular biology, biochemistry and biotechnology

Q Liu, RMP Siloto, R Lehner, SJ Stone… - Progress in lipid …, 2012 - Elsevier
Triacylglycerol (TG) is a storage lipid which serves as an energy reservoir and a source of
signalling molecules and substrates for membrane biogenesis. TG is essential for many …

The life of lipid droplets

TC Walther, RV Farese Jr - Biochimica et Biophysica Acta (BBA)-Molecular …, 2009 - Elsevier
Lipid droplets are the least characterized of cellular organelles. Long considered simple
lipid storage depots, these dynamic and remarkable organelles have recently been …

Domestic-animal genomics: deciphering the genetics of complex traits

L Andersson, M Georges - Nature Reviews Genetics, 2004 - nature.com
One of the'grand challenges' in modern biology is to understand the genetic basis of
phenotypic diversity within and among species. Thousands of years of selective breeding of …

Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle

SDE Park, DA Magee, PA McGettigan, MD Teasdale… - Genome biology, 2015 - Springer
Background Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the
two major domestic extant cattle taxa, B. taurus and B. indicus. While previous genetic …