Respiratory syncytial virus hospitalization and mortality: systematic review and meta‐analysis

RT Stein, LJ Bont, H Zar, FP Polack, C Park… - Pediatric …, 2017 - Wiley Online Library
Background: Respiratory syncytial virus (RSV) is a major public health burden worldwide.
We aimed to review the current literature on the incidence and mortality of severe RSV in …

Prevention and treatment strategies for respiratory syncytial virus (RSV)

D Gatt, I Martin, R AlFouzan, TJ Moraes - Pathogens, 2023 - mdpi.com
Respiratory syncytial virus (RSV) is a leading cause of severe lower respiratory tract
disease, especially in young children. Despite its global impact on healthcare, related to its …

Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response

KH Antunes, JL Fachi, R de Paula, EF da Silva… - Nature …, 2019 - nature.com
Severe respiratory syncytial virus (RSV) infection is a major cause of morbidity and mortality
in infants< 2 years-old. Here we describe that high-fiber diet protects mice from RSV …

Molecular and clinical rationale for therapeutic targeting of interleukin‐5 and its receptor

NA Molfino, D Gossage, R Kolbeck… - Clinical & …, 2012 - Wiley Online Library
Interleukin‐5 is a Th2 homodimeric cytokine involved in the differentiation, maturation,
migration, development, survival, trafficking and effector function of blood and local tissue …

Role of respiratory syncytial virus in pediatric pneumonia

S Bianchini, E Silvestri, A Argentiero, V Fainardi, G Pisi… - Microorganisms, 2020 - mdpi.com
Respiratory viral infections represent the leading cause of hospitalization in infants and
young children worldwide and the second leading cause of infant mortality. Among these …

Clinical and economic hospital burden of acute respiratory infection (BARI) due to respiratory syncytial virus in Spanish children, 2015–2018

F Martinón-Torres, M Carmo, L Platero, G Drago… - BMC Infectious …, 2023 - Springer
Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory infection
(ALRI) in children, causing frequent outpatient visits and hospitalizations. Our study aimed to …

TNF-mediated alveolar macrophage necroptosis drives disease pathogenesis during respiratory syncytial virus infection

LD Santos, KH Antunes, SP Muraro… - European …, 2021 - Eur Respiratory Soc
Respiratory syncytial virus (RSV) is the major cause of acute bronchiolitis in infants under 2
years old. Necroptosis has been implicated in the outcomes of respiratory virus infections …

IL‐33: a tissue derived cytokine pathway involved in allergic inflammation and asthma

DE Smith - Clinical & Experimental Allergy, 2010 - Wiley Online Library
Besides classic T cell‐derived T‐helper type 2 (Th2) cytokines such as IL‐4, IL‐5 and IL‐13,
tissue‐produced cytokines such as thymic stromal lymphopoietin, IL‐25 and IL‐33 are now …

Increased risk of wheeze and decreased lung function after respiratory syncytial virus infection

K Zomer-Kooijker, CK van der Ent, MJJ Ermers… - PloS one, 2014 - journals.plos.org
Background A relationship between hospitalization for respiratory syncytial virus (RSV)
bronchiolitis and asthma development has been suggested in case-control studies …

Burden and severity of children's hospitalizations by respiratory syncytial virus in Portugal, 2015–2018

T Bandeira, M Carmo, H Lopes… - Influenza and Other …, 2023 - Wiley Online Library
Background Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory
infection (ALRI) in young children and is of considerable burden on healthcare systems. Our …