Exosomes are small extracellular vesicles released by almost all cell types in physiological
and pathological conditions. The exosomal potential to unravel disease mechanisms, or to …

Alzheimer's disease (AD), the most common neurodegenerative disorder, is the leading
cause of dementia. Neuritic plaque, one of the major characteristics of AD neuropathology …

Background: Alzheimer's disease (AD) is the most common neurodegenerative disorder,
neuropathologically characterized by aggregates of β-amyloid peptides, which deposit as …

Alzheimer's disease (AD) is one of the utmost chronic neurodegenerative disorders, which is
characterized from a neuropathological point of view by the aggregates of amyloid beta (Aβ) …

The mitochondria are double membrane-bound organelles found in most eukaryotic cells.
They generate most of the cell's energy supply of adenosine triphosphate (ATP). Protein …

The global burden of Alzheimer's disease (AD) is growing. Valiant efforts to develop clinical
candidates for treatment have continuously met with failure. Currently available palliative …

Accumulating evidences show that selenium dietary intake is inversely associated with the
mortality of Alzheimer's disease (AD). Sodium selenate has been reported to reduce …

Evidence suggests that cell cycle activation plays a role in the pathophysiology of
neurodegenerative diseases. Alzheimer's disease is a progressive, terminal …

Human ATP-binding cassette (ABC) transporters mediate a critical function in the cell,
namely the transport of molecules across lipid membranes. Associated to their ubiquitous …

Intrinsically disordered proteins (IDPs) do not have rigid 3D structures, showing changes in
their folding depending on the environment or ligands. Intrinsically disordered proteins are …