Structure, synthesis, biosynthesis, and activity of the characteristic compounds from Ginkgo biloba L.

XG Liu, X Lu, W Gao, P Li, H Yang - Natural Product Reports, 2022 - pubs.rsc.org
Covering: 1928–2021 Ginkgo biloba L. is one of the most distinctive plants to have emerged
on earth and has no close living relatives. Owing to its phylogenetic divergence from other …

Chemistry and Biology of Terpene Trilactones from Ginkgo Biloba

K Strømgaard, K Nakanishi - … Chemie International Edition, 2004 - Wiley Online Library
Ginkgo biloba, the ginkgo tree, is the oldest living tree, with a long history of use in traditional
Chinese medicine. In recent years, the leaf extracts have been widely sold as phytomedicine …

Amyloid-β-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans

Y Wu, Z Wu, P Butko, Y Christen… - Journal of …, 2006 - Soc Neuroscience
Amyloid-β (Aβ) toxicity has been postulated to initiate synaptic loss and subsequent
neuronal degeneration seen in Alzheimer's disease (AD). We previously demonstrated that …

Biflavones from Ginkgo biloba as inhibitors of human thrombin

TR Chen, LH Wei, XQ Guan, C Huang, ZY Liu… - Bioorganic …, 2019 - Elsevier
Ginkgo Biloba leaf extract has been widely used for the prevention and treatment of
thrombosis and cardiovascular disease in both eastern and western countries, but the …

Terpene trilactones from Gingko biloba: from ancient times to the 21st century

K Nakanishi - Bioorganic & medicinal chemistry, 2005 - Elsevier
Ginkgolides were always close to my heart. I continue to be strongly attracted to Ginkgo
biloba, the ginkgolides and bilobalide. Starting in 1963, I became fascinated by these …

Current Perspectives on the Beneficial Role of Ginkgo biloba in Neurological and Cerebrovascular Disorders

KM Nash, ZA Shah - Integrative medicine insights, 2015 - journals.sagepub.com
Ginkgo biloba extract is an alternative medicine available as a standardized formulation,
EGb 761®, which consists of ginkgolides, bilobalide, and flavonoids. The individual …

Ginkgolide B produced endophytic fungus (Fusarium oxysporum) isolated from Ginkgo biloba

Y Cui, D Yi, X Bai, B Sun, Y Zhao, Y Zhang - Fitoterapia, 2012 - Elsevier
To screen the presence of ginkgolide B-producing endophytic fungi from the root bark of
Ginkgo biloba, a total of 27 fungal isolates, belonging to 6 different genus, were isolated …

Heme oxygenase 1, beneficial role in permanent ischemic stroke and in Gingko biloba (EGb 761) neuroprotection

ZA Shah, SE Nada, S Doré - Neuroscience, 2011 - Elsevier
Ginkgo biloba extract, EGb 761, a popular and standardized natural extract, contains 24%
ginkgo-flavonol glycosides and 6% terpene lactones. EGb 761 is used worldwide to treat …

Protective effects of natural compounds against paraquat-induced pulmonary toxicity: the role of the Nrf2/ARE signaling pathway

H Badibostan, N Eizadi-Mood, AW Hayes… - International Journal of …, 2024 - Taylor & Francis
Paraquat (PQ) is a toxic herbicide to humans. Once absorbed, it accumulates in the lungs.
PQ has been well documented that the generation of reactive oxygen species (ROS) is the …

Pharmacological action and mechanisms of ginkgolide B

S Xia, D Fang - Chinese Medical Journal, 2007 - mednexus.org
Objective To review the recent research progress in pharmacological actions and
mechanisms of ginkgolide B. Data sources Information included in this article was identified …