The primary reason for high mortality rates among cancer patients is metastasis, where
tumor cells migrate through the bloodstream from the original site to other parts of the body …

Gene mutation is associated with cancer and the dissemination of circulating biomarkers
through the blood represents a vital transitional step that exemplifies the shift from localized …

Circulating tumor cells (CTCs) hold great potential to answer key questions of how non-
small cell lung cancer (NSCLC) evolves and develops resistance upon anti-PD-1/PD-L1 …

Over the last few years, immunotherapy, in particular, immune checkpoint inhibitor therapy,
has revolutionized the treatment of several types of cancer. At the same time, the uptake in …

Circulating tumor cells (CTCs) that are detached from the tumor can be precursors of
metastasis. The majority of studies focus on enumeration of CTCs from patient blood to …

Simple Summary The clinical success of cancer immunotherapy targeting immune
checkpoints (eg, PD-1, CTLA-4) has ushered in a new era of cancer therapeutics aimed at …

The field of single-cell analysis has advanced rapidly in the last decade and is providing
new insights into the characterization of intercellular genetic heterogeneity and complexity …

Melanoma is among the most aggressive cancers, and its rate of incidence continues to
grow. Early detection of melanoma has been hampered due to the lack of promising markers …

The process of metastasis is characterized by the shedding of tumor cells into the
bloodstream, where they are transported to other parts of the body to seed new tumors …

The combination of liquid biomarkers from a single blood tube can provide more
comprehensive information on tumor development and progression in cancer patients …