Lutein is a xanthophyll carotenoid obtained from various foods, such as dark green leafy
vegetables and egg yolk. Lutein has antioxidant activity and scavenges reactive oxygen …

Hyaluronic acid (HA) is a glycosaminoglycan that was first isolated and identified from the
vitreous body of a bull's eye. HA is ubiquitous in the soft connective tissues of animals and …

Lutein is one of the few xanthophyll carotenoids that is found in high concentration in the
macula of human retina. As de novo synthesis of lutein within the human body is impossible …

The protection of retinal pigment epithelium (RPE) injury plays an important role in the
prevention of or in delaying the pathological progress of retinal degeneration diseases, like …

Cell cycle dysregulation has been implicated in the pathogenesis of neurodegenerative
disorders. Specialised function obligates neuronal cells to subsist in a quiescent state of cell …

Carotenoids are natural lipid-soluble pigments that produce yellow to red colors in plants as
well as providing bright coloration in vegetables and fruits. Lutein belongs to the xanthophyll …

Age-related macular degeneration (AMD) is central vision loss with aging, was the fourth
main cause of blindness in 2015, and has many risk factors, such as cataract surgery …

Diabetic retinopathy (DR) is a major cause of acquired blindness among working adults. The
retinal pigment epithelium (RPE), constitutes an outer blood-retinal barrier, is vastly affected …

Aiming to enhance therapeutic efficiency of lutein, lutein loaded chitosan-sodium alginate
(CS-SA) based nanocarrier system (LNCs) were prepared and evaluated for lutein …

Retinal pigment epithelial (RPE) cells are central to retinal health and homoeostasis.
Oxidative stress-induced damage to the RPE occurs as part of the pathogenesis of age …